Results 121 to 130 of about 621,620 (285)

Revisiting PFA-mediated tissue fixation chemistry: <i>FixEL</i> enables trapping of small molecules in the brain to visualize their distribution changes. [PDF]

Chem, 2023
Nonaka H, Mino T, Sakamoto S, Oh JH, Watanabe Y, Ishikawa M, Tsushima A, Amaike K, Kiyonaka S, Tamura T, Aricescu AR, Kakegawa W, Miura E, Yuzaki M, Hamachi I.   +14 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Survivorship and Reoperation of 324 Consecutive Isolated or Combined Arthroscopic Meniscal Allograft Transplants Using Soft Tissue Fixation. [PDF]

Am J Sports Med, 2023
Grassi A, Di Paolo S, Coco V, Romandini I, Filardo G, Lucidi GA, Marcacci M, Zaffagnini S.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Alternative tissue fixation for combined histopathological and molecular analysis in a clinically representative setting. [PDF]

Histochem Cell Biol, 2021
Meecham A, Miranda E, Morris HT, Hair J, Oien KA, Gerrard G, Guppy N, Mooney D, Shaw EC, Ashton-Key M, Lees R, Flanagan A, Rodriguez-Justo M.   +12 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Vital Perfusion-Fixation Technique Through Carotid Arteries for Preparation of Histologic Sections from Periodontium and Jaw Bone of Dog

مجله دانشکده دندانپزشکی اصفهان, 2005
processing of tissues before histologic slices is necessary for preparation of proper histologic sections in animal studies. Fixation is one of the most important and early laboratory stages of tissue processing.
AA - Basiri, M Atabaki, Sh Adibi
doaj  

Quantitative assessment of fixation strength in combined thread lifting: Comparative analysis of bidirectional-multidirectional versus double bidirectional thread combinations

JPRAS Open
Background: The efficacy of thread lifting procedures for facial rejuvenation is significantly influenced by thread fixation strength and tissue stabilization capabilities. This study presents a quantitative biomechanical comparison between bidirectional
Kyu-Ho Yi, Soo Yeon Park, Jovian Wan, Jong Keun Song, Jin-Hyun Kim, Erik Koppert, Jae Young Kim   +6 more
doaj   +1 more source

Making a science out of preanalytics: An analytical method to determine optimal tissue fixation in real-time. [PDF]

PLoS One, 2021
Bauer DR, Leibold T, Chafin DR.
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source