Results 41 to 50 of about 4,427,559 (374)

CryoNuSeg: A Dataset for Nuclei Instance Segmentation of Cryosectioned H&E-Stained Histological Images [PDF]

open access: yes, 2021
Nuclei instance segmentation plays an important role in the analysis of Hematoxylin and Eosin (H&E)-stained images. While supervised deep learning (DL)-based approaches represent the state-of-the-art in automatic nuclei instance segmentation, annotated datasets are required to train these models. There are two main types of tissue processing protocols,
arxiv   +1 more source

Formalin fixation at low temperature better preserves nucleic acid integrity. [PDF]

open access: yesPLoS ONE, 2011
Fixation with formalin, a widely adopted procedure to preserve tissue samples, leads to extensive degradation of nucleic acids and thereby compromises procedures like microarray-based gene expression profiling.
Gianni Bussolati   +4 more
doaj   +1 more source

Three Dimensional Optimization of Scaffold Porosities for Bone Tissue Engineering [PDF]

open access: yesarXiv, 2021
We consider the scaffold design optimization problem associated to the three dimensional, time dependent model for scaffold mediated bone regeneration considered in Dondl et al. (2021). We prove existence of optimal scaffold designs and present numerical evidence that optimized scaffolds mitigate stress shielding effects from exterior fixation of the ...
arxiv  

A Study on the Stainability and DNA Conservation of Tissue Slides according to Fixation Time and Temperature

open access: yesKorean Journal of Clinical Laboratory Science
In this paper, the factors affecting tissues during fixation on slides were determined by changing the tissue type, fixation time, and temperature. Also, stainability and DNA conservation were evaluated.
Da-som JEONG
doaj   +1 more source

New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue

open access: yesMolecular Brain, 2022
Adult neurogenesis, the proliferation and integration of newly generated neurons, has been observed in the adult mammalian hippocampus of many species. Numerous studies have also found adult neurogenesis in the human hippocampus, but several recent high ...
Dylan J. Terstege   +3 more
doaj   +1 more source

Comparing 3 Different Techniques of Patella Fracture Fixation and Their Complications

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2019
Introduction: Patella fractures managed by fixation with metal implants often cause local soft tissue irritation and necessitate implant removal. An alternative is to utilize suture-based fixation methods.
Graham Ka-Hon Shea MBBS, PhD   +5 more
doaj   +1 more source

Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

open access: yesEuropean Journal of Histochemistry, 2013
Staining of mast cells (MCs), including porcine ones, is critically dependent upon the fixation and staining technique. In the pig, mucosal and submucosal MCs do not stain or stain only faintly after formalin fixation.
J. Rieger   +4 more
doaj   +1 more source

Formalin Fixation as Tissue Preprocessing for Multimodal Optical Spectroscopy Using the Example of Human Brain Tumour Cross Sections

open access: yesJournal of Spectroscopy, 2021
Characterization of brain tumours requires neuropathological expertise and is generally performed by histological evaluation and molecular analysis.
Mona Stefanakis   +15 more
doaj   +1 more source

Simulasi Pengaruh Jumlah Lubang pada Ring Fiksasi Eksternal untuk Tulang Tibia

open access: yesSemesta Teknika, 2018
External fixation is a device that is placed out of soft tissue. External fixation device is used to heal open fracture. Open fracture is fracture that soft tissue is broken. That device consist of pin, rod, and clamp. We should pay attention of external
Krisdiyanto Krisdiyanto
doaj   +1 more source

Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies

open access: yesPharmaceuticals, 2022
Fixation of samples is broadly used prior to the histological evaluation of tissue samples. Though recent reports demonstrated the ability to use fixed tissues for mass spectrometry imaging (MSI) based proteomics, glycomics and tumor classification ...
Andreas Dannhorn   +7 more
doaj   +1 more source

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