Results 11 to 20 of about 116,272 (297)

The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs. [PDF]

Pulm Med, 2022
Tissue inhibitors of matrix metalloproteinases (TIMP) are a family of four endogenous proteins that primarily function to inhibit the activities of proteases such as the matrix metalloproteinases (MMP).
Costanzo L, Soto B, Meier R, Geraghty P.
europepmc   +5 more sources

Release of tissue inhibitor of metalloproteinase-2 from alginate microcapsule encapsulating genetically engineered cells. [PDF]

Int J Nanomedicine, 2013
Yeon Seong Kim,1,* Young-Il Jeong,2,* Shu-Guang Jin,2 Jian Pei,2 Min Wen,2 In-Young Kim,1 Kyung-Sub Moon,1 Tae-Young Jung,1 Hyang-Hwa Ryu2, Shin Jung1–3 1Department of Neurosurgery, 2Brain Tumor Research Laboratory, 3Chonnam National University ...
Kim YS, Jeong YI, Jin SG, Pei J, Wen M, Kim IY, Moon KS, Jung TY, Ryu HH, Jung S.   +9 more
europepmc   +4 more sources

The Contribution of Tissue Inhibitor of Metalloproteinase-2 Genotypes to Breast Cancer Risk in Taiwan. [PDF]

Life (Basel), 2023
Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an endogenous inhibitor of matrix metalloproteinase-2 and is highly expressed in breast cancer (BC) cases at diagnosis.
Wang YC, He JL, Tsai CL, Tzeng HE, Chang WS, Pan SH, Chen LH, Su CH, Lin JC, Hung CC, Bau DT, Tsai CW.   +11 more
europepmc   +2 more sources

Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients. [PDF]

J Thorac Dis, 2017
Assessment of serum extracellular matrix (ECM) metalloproteinase MMP-2 and tissue inhibitor of matrix metalloproteinase TIMP-2 concentrations in non-small cell lung carcinoma (NSCLC) patients considering TNM staging. Assessment of the prognostic value of MMP-2 and TIMP-2 concentrations in NSCLC patients.The study group consisted of 81 NSCLC patients ...
Drzewiecka-Jędrzejczyk M, Wlazeł R, Terlecka M, Jabłoński S.   +3 more
europepmc   +4 more sources

The Distribution of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-4 in Psoriatic Skin [PDF]

British Journal of Medicine and Medical Research, 2015
Aims: To evaluate the appearance and distribution of matrix metalloproteinase-2 (MMP-2), tissue inhibitor of metalloproteinase-2 (TIMP-2) and tissue inhibitor of metalloproteinase-4 (TIMP-4) in lesional skin biopsies of psoriasis patients. Study Design: Observational study.
Elga Sidhom, Mara Pilmane, Janis Kisis
openaire   +3 more sources

Relationship between Circulating Serpina3g, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinase-1 and -2 with Chronic Obstructive Pulmonary Disease Severity

Biomolecules, 2019
Chronic obstructive pulmonary disease (COPD) is influenced by genetic and environmental factors. A protease-antiprotease imbalance has been suggested as a possible pathogenic mechanism for COPD.
Hafize Uzun, Pelin Uysal, Uzun Hafize
exaly   +3 more sources

Increased Circulating Tissue Inhibitor of Metalloproteinase-2 Is Associated With Resistant Hypertension. [PDF]

J Clin Hypertens (Greenwich), 2016
Resistant hypertension (RH) is associated with organ damage and cardiovascular risk. Evidence suggests the involvement of matrix metalloproteinase 2 (MMP‐2) and tissue inhibitor of metalloproteinase 2 (TIMP‐2) in hypertension and in cardiovascular remodeling. The aim of this study was to assess the levels of MMP‐2 and TIMP‐2 in RH and its relation with
Sabbatini AR, Barbaro NR, de Faria AP, Modolo R, Ritter AM, Pinho C, Amorim RF, Fontana V, Moreno H.   +8 more
europepmc   +5 more sources

Mitral tissue inhibitor of metalloproteinase 2 is associated with mitral valve surgery outcome. [PDF]

PLoS One, 2014
BACKGROUND: Matrix metalloproteinases play a role in regulating cardiac remodeling. We previously reported an association between tissue inhibitor of metalloproteinase 2 (TIMP-2) expression and mitral valve (MV) disease.
Lin TH, Yang SF, Chiu CC, Su HM, Voon WC, Chai CY, Lai WT, Sheu SH.   +7 more
europepmc   +2 more sources

Molecular mechanisms of tissue inhibitor of metalloproteinase 2 in the tumor microenvironment. [PDF]

Mol Cell Ther, 2014
There has been a recent paradigm shift in the way we target cancer, drawing a greater focus on the role of the tumor microenvironment (TME) in cancer development, progression and metastasis. Within the TME, there is a crosstalk in signaling and communication between the malignant cells and the surrounding extracellular matrix. Matrix metalloproteinases
Remillard TC, Bratslavsky G, Jensen-Taubman S, Stetler-Stevenson WG, Bourboulia D.   +4 more
europepmc   +4 more sources

Tissue inhibitor of metalloproteinase-2 predicts early allograft dysfunction after liver transplantation. [PDF]

Eur J Med Res
Background The lack of objective criteria to assess graft integrity represents a major impediment to the acceptance of livers of limited quality as a way to increase the donor pool in liver transplantation.
von Horn C, Zlatev H, Malkus L, Minor T.
europepmc   +2 more sources