Results 51 to 60 of about 116,272 (297)

Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients

Folia Histochemica et Cytobiologica, 2012
The positive expression of MMP-2 and TIMP-2 were found in esophageal cancer (EC) tissue and correlated with cancer stage and clinico-pathological features of tumor and patients' survival. However, little is known about serum levels of those proteins in EC patients. The aim of the present study was to investigate the diagnostic significance of MMP-2 and
Magdalena, Groblewska, Barbara, Mroczko, Miroslaw, Kozlowski, Jacek, Niklinski, Jerzy, Laudanski, Maciej, Szmitkowski   +5 more
openaire   +3 more sources

Immunohistochemical Correlation of Matrix Metalloproteinase-2 and Tissue Inhibitors of Metalloproteinase-2 in Tobacco Associated Epithelial Dysplasia [PDF]

Disease Markers, 2014
Aim. To study the immunohistochemical expression of matrix metalloproteinase and tissue inhibitors of matrix metalloproteinase-2 in different histological grades of tobacco associated epithelial dysplasia and correlate the association between these proteases.
Dipshikha Bajracharya, Bijayatha Shrestha, Asha Kamath, Aparna Menon, Raghu Radhakrishnan   +4 more
openaire   +2 more sources

Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis [PDF]

Nephron, 2020
<b><i>Introduction:</i></b> Urinary tissue inhibitor of metalloproteinases (TIMP)-2 has been identified as a predictive marker for acute kidney injury (AKI), including sepsis-associated AKI (S-AKI). Whether TIMP-2 might be causally related to AKI and hence represent a viable drug target is unclear.
Xiaoyan, Wen, Jicheng, Zhang, Xiaojian, Wan, Alicia A, Frank, Xin, Qu, John A, Kellum   +5 more
openaire   +2 more sources

Dependence of TIMP-1 plasma levels on preanalytical specimen handling [PDF]

, 2008
Background: Tissue inhibitor of metalloproteinases-1 (TIMP-1) in blood might be a helpful biomarker in various diseases. However, various authors report that TIMP-1 is dependent on preanalytical procedures.
Doss, Robert, Dorothea Nagel, Barry Dowell, Stieber, Petra, Marie Dresse, Dowell, Barry, Dresse, Marie, Robert Doss, Davis, Gerard, Ganser, Eva-Maria, Gerard Davis, Eva-Maria Ganser, Nagel, Dorothea, Petra Stieber   +13 more
core   +1 more source

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]

Iranian Journal of Otorhinolaryngology, 2019
Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk, Piotr Sawicki, Lukasz Szylberg, Magdalena Bodnar, Andrzej Marszalek   +4 more
doaj   +1 more source

Altered expression of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cervical disc herniation patients

Genetics and Molecular Research, 2016
The aim of the current study was to examine matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) expression in patients with cervical disc herniation (CDH). A total of 127 specimens from CDH patients undergoing posterior spinal surgery were obtained for the case group, which was divided into three subgroups: lateral ...
H M, Zhuang, G T, Xu, S F, Wen, Y Y, Guo, Q, Huang   +4 more
openaire   +2 more sources

Matrix metalloproteinase‐2 promoter and tissue inhibitor of metalloproteinase‐2 gene polymorphisms in non‐Hodgkin's lymphoma [PDF]

International Journal of Cancer, 2011
AbstractSingle nucleotide polymorphisms in the promoter regions of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMP) genes are associated with an adverse outcome in some cancers. We examined three polymorphisms: −1306C/T and −735C/T in MMP‐2 and −418G/C in the TIMP‐2 gene, using chain reaction restriction fragment ...
Lan-Ping, Diao, Hui, Ma, Guang-Chuan, Wei, Tao, Li, Hai-Sheng, Liu, Li-Hong, Liu, Li-Li, Wu, Gui-Min, Zhao, Yu-Huan, Gao   +8 more
openaire   +2 more sources

IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway

Stem Cells International, 2018
Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear.
Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang   +5 more
doaj   +1 more source

Role of Oxidative Stress and Genetic Polymorphism of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in COPD

Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, 2023
Article in press withdrawn by publisher.
Poonam, Sangwan, Huma, Quasimi, Jai Gopal, Sharma, Mohammad Anwar, Habib, Mohammad Iqbal, Alam   +4 more
openaire   +2 more sources

Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]

, 2012
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Notohamiprodjo, Susan, Jaeckel, Carsten, Djafarzadeh, Roghieh, Hofstetter, Monika, Nelson, Peter J., Rieth, Nicole   +5 more
core   +1 more source