Results 141 to 150 of about 599,368 (371)
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
, 2003 Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +9 more
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Brain : a journal of neurology, 2012 The neurovascular unit provides a dynamic interface between the circulation and central nervous system. Disruption of neurovascular integrity occurs in numerous brain pathologies including neurotrauma and ischaemic stroke. Tissue plasminogen activator is
M. Sashindranath +15 more
semanticscholar +1 more source
Dose de-escalation of intrapleural tissue plasminogen activator therapy for pleural infection. The alteplase dose assessment for Pleural infection Therapy project [PDF]
, 2017 Rationale: Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10 mg and DNase 5 mg administered twice daily has been shown in randomized and open-label studies to successfully manage over 90% of patients with pleural infection ...
Bintcliffe, Oliver +10 more
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Annals of Neurology, 2011 Risk of intracerebral hemorrhage is the primary factor limiting use of tissue plasminogen activator (tPA) for stroke. Clinical studies have established an association between admission hyperglycemia and the risk of hemorrhage with tPA use, independent of
S. Won +4 more
semanticscholar +1 more source
ChemMedChem, Accepted Article.Kallikrein‐related peptidases are a family of serine proteases which loss of activity regulation has been particularly linked to neurodegenerative diseases. Moreover, iron overload is also a key process in some of these leading pathological conditions, particularly Alzheimer’s disease.
Rilès Boumali +11 more
wiley +1 more source
Decrease of fibrinolytic potential in the occurrence of cerebral ischemia [PDF]
Journal of Medical Biochemistry, 2008 One of the most present clinical manifestations of long and progressive atherothrombotic occurrences is the ischemic cerebrovascular insult, one of the leading causes of death and illness in the world.
Vučković Biljana +4 more
doaj
Endogenous Fibrinolysis : An Important Mediator of Thrombus Formation and Cardiovascular Risk [PDF]
, 2015 © 2015 BY THE AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION. PUBLISHED BY ELSEVIER INC.Most acute cardiovascular events are attributable to arterial thrombosis.
Gorog, Diana A, Okafor, Osita N
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Recombinant Tissue Plasminogen Activator for the Treatment of Acute Ischemic Stroke
Proceedings, 2011 The use of recombinant tissue plasminogen activator (rtPA) has been the standard of care for treatment of acute ischemic stroke for several years. Studies evaluating the efficacy, safety, and optimal timing of rtPA use are ongoing.
J. Roth
semanticscholar +1 more source
Current and novel biomarkers in cardiogenic shock
European Journal of Heart Failure, EarlyView.A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko +5 more
wiley +1 more source
Minactivin expression in human monocyte and macrophage populations [PDF]
, 1985 Adherent monolayer cultures of human blood monocytes, peritoneal macrophages, bone marrow macrophages, and colonic mucosa macrophages were examined for their ability to produce and secrete minactivin, a specific inactivator of urokinase-type plasminogen ...
Allan, W +7 more
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