Results 151 to 160 of about 2,071,373 (281)

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

The Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min, Órlaith C. Henry, Luke A. J. O'Neill   +2 more
wiley   +1 more source

Subretinal Tissue Plasminogen Activator Injection Using a Nanovitreoretinal Device for Massive Submacular Hemorrhage: A Retrospective Case Series. [PDF]

Korean J Ophthalmol
Chun J, Choi YJ, Kim TY, Park SI, Lee SM, Choi EY, Lee J, Kim M.   +7 more
europepmc   +1 more source

COMPARABLE RESULTS OF SUBRETINAL INJECTION AND INTRAVITREAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF SUBMACULAR HEMORRHAGE: A Meta-Analysis of Efficacy. [PDF]

Retina
Zhang L, Zhang Y, Si W, Wang X, Jiang S, Qin X.   +5 more
europepmc   +1 more source

Regulation of the acute release of tissue-type plasminogen activator from the endothelium by coagulation activation products

, 1992
Chemicals/CAS: Blood Coagulation Factors; Tissue Plasminogen Activator, EC 3.4.21 ...
Emeis, J.J.
core  

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1289-1297, December 2026.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Catheter-Directed Recombinant Tissue Plasminogen Activator for Treatment of Aortic Root and Coronary Artery Thrombosis in Single Ventricle Patients: A Case Series. [PDF]

J Soc Cardiovasc Angiogr Interv
Pacella J, Matoq A, Batlivala S, Shahanavaz S.   +3 more
europepmc   +1 more source

Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1455-1463, December 2026.
ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su, Yao Wei, Cheng Liu, Yafei Gao, Xiaolong Ma, Yongxin Li, Rui Qiao   +6 more
wiley   +1 more source

Integration of Chemical Probes and Degradomics Reveals That Cathepsin B Functions Primarily as a Dipeptidyl Carboxypeptidase in Macrophages

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
An integrated chemical biology and degradomics approach reveals the proteolytic landscape of cathepsin B in mouse macrophages. Z‐RK‐AOMK perturbs the cysteine cathepsin network and reveals that cathepsin B predominantly exhibits dipeptidyl carboxypeptidase activity in cells.
Kai‐Qi Yek, Francesca L. Apolloni, Bangyan Xu, Nghi H. Nguyen, Alexander R. Ziegler, Nichollas E. Scott, Brad E. Sleebs, Laura E. Edgington‐Mitchell   +7 more
wiley   +1 more source

Mechanical Aortic Valve Thrombosis: Treatment With Tissue Plasminogen Activator. [PDF]

JACC Case Rep
Munawar G, Gupta V, Laiq Z, Sleik K.
europepmc   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source