Results 171 to 180 of about 2,071,373 (281)

Sturge-Weber Syndrome With Leptomeningeal Angiomatosis and Middle Cerebral Artery Narrowing Treated With Intravenous Tissue Plasminogen Activator (IV tPA): A Case Report. [PDF]

Cureus
Kaur G, Sardana S, Mateti NR, Debiec J, Saim M, Abdullah H, Singh R, Wright D, Cerejo R.   +8 more
europepmc   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Thrombolytic therapy efficacy in cardiopulmonary resuscitation: Investigating the effect of recombinant tissue plasminogen activator (Review). [PDF]

Mol Med Rep
Zhang W, Pan Y, Ding J, Xu D, Wang W.
europepmc   +1 more source

Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models

MedComm, Volume 7, Issue 11, November 2026.
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini, Rosalba La Grotta, Alessia Metallo, Francesca Carreras, Chiara Frigé, Giulia Matacchione, Angelica Giuliani, Jacopo Sabbatinelli, Fabiola Olivieri, Francesca Rispoli, Lorenzo Drago, Cesare Celeste Berra, Raffaele Marfella, Giuseppe Paolisso, Giuseppe Matarese, Claudio Procaccini, Ilaria Spatocco, Giorgia Mele, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo   +20 more
wiley   +1 more source

Neuroserpin, Tissue Plasminogen Activator, Brain-Derived Neurotrophic Factor and Interleukin-6 Serum Levels in Patients with Bipolar Disorder. [PDF]

Noro Psikiyatr Ars
Ünver H, Karadağ H, Aydın FN, Özkaya G, Erzin G.   +4 more
europepmc   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

Pharmaceutical Compatibility of Tissue Plasminogen Activator and DNase.

Respiration
Frencken JF, Hassanzai M, Hoek RAS, van der Sijs HH.   +3 more
europepmc   +1 more source

Intravenous tissue plasminogen activator in functional stroke mimics. [PDF]

Postep Psychiatr Neurol
Kowalska MM, Michałowska MM, Leńska-Mieciek MM.   +2 more
europepmc   +1 more source

MKP‐2 Genetic Depletion Modulates Adipose Lipid Composition, Cellular Senescence, and Aging in Mice

Aging Cell, Volume 25, Issue 11, November 2026.
Excess white adipose tissue (WAT) accumulation promotes aging by increasing the risk of insulin resistance and chronic diseases and reduced lifespan. MKP‐2 deficiency protects against premature senescence in cells and WAT and is associated with adipose lipid remodeling, improved metabolic health, and longer lifespan.
Morgan Welch, Nabin Ghimire, Shauri Smith, Cassandra Secunda, Alexis Fink, Alissar Sleiman, Laura Chambliss, Christopher Pinckard, Chloe Reyes, Priya Katta, Anna Ai, Benjamin R. Harrison, Ahmed Lawan   +12 more
wiley   +1 more source

One-Year Outcomes After Intravenous Recombinant Tissue Plasminogen Activator for Ischemic Stroke: A Real-World Study. [PDF]

CNS Neurosci Ther
Xue R, Gong X, Huang Y, Zhong W, Jin H, Chen Z, Chen Y, Yan S, Hu H, Yuan C, Lou M.   +10 more
europepmc   +1 more source