Results 181 to 190 of about 579,513 (302)

Tissue plasminogen activator modified thromboelastography identifies fibrinolysis resistance in dogs with immune-mediated hemolytic anemia. [PDF]

Front Vet Sci
Goggs R, Davis S, Brooks MB.
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, Volume 13, Issue 41, 22 July 2026.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Enhancing Thrombolysis Safety in Post-Acute Ischemic Stroke with Tissue Plasminogen Activator-Associated Microparticles. [PDF]

ACS Nano
Spanò R, Portioli C, Geroski T, Felici A, Palange AL, Gawne PJ, Mamberti S, Avancini G, Palomba R, Bonnard T, Moore TL, Del Sette M, Filipovic N, Vivien D, Decuzzi P.   +14 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, Volume 13, Issue 41, 22 July 2026.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Serum tissue plasminogen activator after cycling with blood flow restriction. [PDF]

Vasc Biol
Landers JB, Allen M, Oladele I, Lowe L, Ali N, Rainey J, Fletcher J, Landers K.   +7 more
europepmc   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1871-1881, July 2026.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn, Hannah K. Windsor, Zachary Schmitz, Nathaniel Cheung, Ebube Agwaramgbo, Benjamin J. Hackel   +5 more
wiley   +1 more source

Poor long-term fellow-eye outcomes after vitrectomy with subretinal tissue plasminogen activator for AMD-related submacular hemorrhage. [PDF]

Graefes Arch Clin Exp Ophthalmol
Fried S, Vorobichik Berar O, David D, Arazi M, Klain B, Cohen GY, Fogel Levin M, Platner E, Katz G, Hostovsky A.   +9 more
europepmc   +1 more source

Prognostic Factors in Acute Ischemic Stroke With a Decreased Estimated Glomerular Filtration Rate

Brain and Behavior, Volume 16, Issue 7, July 2026.
ABSTRACT Introduction Intra‐arterial thrombectomy (IAT), which is widely used to treat acute ischemic stroke, occasionally results in adverse outcomes. IAT‐associated risks in patients with decreased estimated glomerular filtration rate (eGFR) remain undefined.
Chang Hyeon Kim, Hyun Uk Lee, Byoung‐Soo Shin, Hyun Goo Kang   +3 more
wiley   +1 more source

Tissue Plasminogen Activator (tPA) Use in Persistent Loculated Ascites. [PDF]

Cureus
Ali KM, Molloy R, Friedman A, Srikureja W, Bent C, Garrison RC.   +5 more
europepmc   +1 more source

Angioscopy Visualized a Residual Free‐Floating Thrombus in Mild Carotid Artery Stenosis Following Acute MCA Occlusion: A Case Report

Catheterization and Cardiovascular Interventions, Volume 108, Issue 1, Page 1-5, July 1, 2026.
ABSTRACT Carotid free‐floating thrombus (CFFT) is a rare yet severe cause of the ischemic stroke. Early identification and appropriate management are crucial to prevent recurrent embolic events. A 76‐year‐old man experienced sudden left‐sided hemiparesis and dysarthria.
Hirofumi Matsubara, Yusuke Egashira, Yukiko Enomoto, Tsuyoshi Izumo   +3 more
wiley   +1 more source