Results 261 to 270 of about 162,477 (300)

Monoclonal Antibody Therapies in Alzheimer's Disease: A Guide for Emergency Physicians

Emergency Medicine Australasia, Volume 37, Issue 6, December 2025.
ABSTRACT Whilst the advent of novel disease‐modifying medications for Alzheimer's disease represents potential benefit for patients and caregivers, they may be associated with adverse events that present important considerations for emergency and primary care. This article seeks to highlight some of the challenges Emergency Departments may encounter in
Scott Wrigley, Andrew L. H. Huynh, Sanka Amadoru, Henry Zeimer, Irene Tan, Michael Woodward, George Braitberg, Paul Andrew Yates   +7 more
wiley   +1 more source

Pharmacokinetics and pharmacodynamics of low doses of recombinant tissue plasminogen activator to establish a model for biosimilarity comparisons. [PDF]

Res Pract Thromb Haemost
Derhaschnig U, Buchtele N, Steiner MM, Drucker C, Firbas C, Schörgenhofer C, Gelbenegger G, König F, Jilma B, Kovacevic Miljevic KD.   +9 more
europepmc   +1 more source

Maternal Diet‐Induced Excess Adiposity in Mice Disrupts Mid‐Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling

Acta Physiologica, Volume 241, Issue 12, December 2025.
ABSTRACT Aim Maternal excess adiposity (i.e., overweight/obesity) is linked to impaired uteroplacental perfusion, compromised placental development, and increased risk of adverse pregnancy outcomes. Inflammation and immune dysregulation accompanying excess adiposity may disrupt leukocyte‐mediated tissue remodeling and immunoregulation, contributing to ...
Christian J. Bellissimo, Erica Yeo, Tatiane A. Ribeiro, Patrycja A. Jazwiec, Chethana Ellewela, Jaskiran Bains, Ariana E. Lewis, Katherine M. Kennedy, Ali A. Ashkar, Alexander G. Beristain, Dawn M. E. Bowdish, Deborah M. Sloboda   +11 more
wiley   +1 more source

A novel technique for extensive submacular hemorrhage using high-dose tissue plasminogen activator. [PDF]

Indian J Ophthalmol
Chauhan K, Narayanan R.
europepmc   +1 more source

Serum Proteomic Profiling Uncovers LGALS3BP as a Potential Biomarker for Idiopathic Pulmonary Arterial Hypertension

The Clinical Respiratory Journal, Volume 19, Issue 12, December 2025.
Serum proteomic analysis revealed 114 differentially expressed proteins in IPAH. LGALS3BP, validated as elevated by ELISA, emerges as a new biomarker for pathogenesis and translation. ABSTRACT Background Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and fatal disease characterized by pathological pulmonary vascular remodeling and ...
Mingfei Li, Qi Jin, Wenzhi Pan, Dan Tian, Peng Wang, Dandan Chen, Yuan Zhang, Shasha Chen, Daxin Zhou, Lihua Guan, Junbo Ge   +10 more
wiley   +1 more source

Using Rotational Thromboelastometry (ROTEM) to Evaluate Coagulation Status After Intrapleural Recombinant Tissue Plasminogen Activator (rtPA) Administration in Regional Anesthesia. [PDF]

Cureus
DeLeon A, Tureanu L, Vetter O, Liu T, Korula R, Garcia Tomas V, Asher Y.   +6 more
europepmc   +1 more source

Impact of Stress Hyperglycemia Ratio on Adverse Outcomes in Patients With Chronic Thromboembolic Pulmonary Hypertension

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Prognostic assessment of chronic thromboembolic pulmonary hypertension (CTEPH) remains challenging. Stress hyperglycemia, a condition where glucose metabolism is regulated during stress, has been regarded as an indicator of acute hyperglycemia. The stress hyperglycemia ratio (SHR) serves as a more precise marker for this state.
Yijia Wang, Xin Li, Zhihua Huang, Anqi Duan, Sicheng Zhang, Qi Wang, Sicong Li, Luyang Gao, Qing Zhao, Tao Yang, Zhihui Zhao, Qin Luo, Zhihong Liu   +12 more
wiley   +1 more source

Tissue Plasminogen Activator or Perfluoropropane for Submacular Hemorrhage in Age-Related Macular Degeneration: A Factorial Randomized Clinical Trial.

JAMA Ophthalmol
Murphy GSP, Saleh A, Ayis S, Cheema MR, Mehta A, Steel DH, Membrey L, Costen M, Jackson TL.   +8 more
europepmc   +1 more source

Conservative Treatment of Empyema Formation Following Intrathoracic Rib Fixation With Antibiotics and Tissue Plasminogen Activator/Dornase. [PDF]

J Med Cases
Malkoc A, Mamoun L, Vignaroli K, Gill H, Barmanwalla A, Phan A, Daoud A, Nguyen A, Woodward B.   +8 more
europepmc   +1 more source

Tissue-type-plasminogen-activator-associated fibrinolysis in orthotopic liver transplantation [PDF]

, 1989
Bontempo, FA, Kang, YG, Knot, EAR, Lewis, JH, Porte, RJ, Starzl, TE   +5 more
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