Results 241 to 250 of about 2,071,373 (281)

Tissue Plasminogen Activator Activity in Prostatic Cancer

European Urology, 1984
19 patients with carcinoma of the prostate and 6 controls with hyperplasia of the prostate, have been investigated to elucidate the relationship between tumor fibrinolytic activity, the degree of malignancy, tumor stage and metastatic spread. Significantly (p less than 0.001) higher tissue plasminogen activator activities were found in metastatic ...
A, Köller, J, Kirchheimer, H, Pflüger, B R, Binder   +3 more
openaire   +2 more sources

Importance of the interaction between plasminogen and fibrin for plasminogen activation by tissue-type plasminogen activator

Thrombosis Research, 1984
The potentiating effect of fibrin monomer on plasminogen activation by tissue-type plasminogen activator is much more important with lys-plasminogen than with mini-plasminogen (which lacks the high affinity lysine-binding site important for binding to fibrin).
F W, Dunn, K, Deguchi, J, Soria, C, Soria, H R, Lijnen, G, Tobelem, J, Caen   +6 more
openaire   +2 more sources

Tissue Plasminogen Activator (t-PA)

Therapeutic Drug Monitoring, 1993
Tissue plasminogen activator (t-PA) developed from recombinant DNA technology is a highly effective thrombolytic agent. Its main clinical application is in the treatment of acute myocardial infarction (MI), with most beneficial results occurring in patients treated early after the onset of symptoms. When t-PA was compared with other thrombolytic agents,
J, Madhani, H, Movsowitz, M N, Kotler
openaire   +2 more sources

Ontogenesis of Tissue Plasminogen Activator in the Human

Thrombosis and Haemostasis, 1971
SummaryThe ontogenesis of tissue plasminogen activator in various tissues was studied in 10 embryos and 58 foetuses with a histochemical method.The first appearance of activator activity was seen in a 4-weeks old embryo. At 8-9 weeks it was seen in the eye, meninges, heart, lungs, kidney and vena cava. In the foetal heart high activity was found in the
B, Astedt, M, Pandolfi
openaire   +2 more sources

Plasminogen and Tissue Plasminogen Activator Interact with Antithrombin III

Thrombosis Research, 2000
Human antithrombin III was demonstrated to bind plasminogen specifically in a time and concentration-dependent manner. The above binding was also confirmed using ligand western blot assays. The interaction of plasminogen was significantly (>90%) inhibited by lysine, indicating the involvement of kringles in binding antithrombin III.
openaire   +2 more sources

Histochemistry of Tissue Plasminogen Activator

Thrombosis and Haemostasis, 1975
openaire   +2 more sources

Treatment With Tissue Plasminogen Activator in the Golden Hour and the Shape of the 4.5-Hour Time-Benefit Curve in the National United States Get With the Guidelines-Stroke Population

Circulation, 2017
Jeffrey L. Saver, James C Grotta
exaly  

Tissue Plasminogen Activator and Other Risk Factors as Predictors of Cardiovascular Events in Patients With Severe Angina Pectoris.

European Heart Journal, 1991
T K Nilsson, J H Jansson
exaly  

Eligibility for Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke

Stroke, 2004
Pancioli Arthur, Edward Jauch, Brett M. Kissela   +2 more
exaly  

Risk of Intracranial Hemorrhage Following Intravenous tPA (Tissue-Type Plasminogen Activator) for Acute Stroke Is Low in Children

Stroke, 2020
Michael M Dowling, Adam Kirton, Hugh J. McMillan   +2 more
exaly