Results 281 to 290 of about 165,123 (342)

Pharmacokinetics and pharmacodynamics of low doses of recombinant tissue plasminogen activator to establish a model for biosimilarity comparisons. [PDF]

Res Pract Thromb Haemost
Derhaschnig U, Buchtele N, Steiner MM, Drucker C, Firbas C, Schörgenhofer C, Gelbenegger G, König F, Jilma B, Kovacevic Miljevic KD.   +9 more
europepmc   +1 more source

Tissue Plasminogen Activator or Perfluoropropane for Submacular Hemorrhage in Age-Related Macular Degeneration: A Factorial Randomized Clinical Trial.

JAMA Ophthalmol
Murphy GSP, Saleh A, Ayis S, Cheema MR, Mehta A, Steel DH, Membrey L, Costen M, Jackson TL.   +8 more
europepmc   +1 more source

Conservative Treatment of Empyema Formation Following Intrathoracic Rib Fixation With Antibiotics and Tissue Plasminogen Activator/Dornase. [PDF]

J Med Cases
Malkoc A, Mamoun L, Vignaroli K, Gill H, Barmanwalla A, Phan A, Daoud A, Nguyen A, Woodward B.   +8 more
europepmc   +1 more source

Using Rotational Thromboelastometry (ROTEM) to Evaluate Coagulation Status After Intrapleural Recombinant Tissue Plasminogen Activator (rtPA) Administration in Regional Anesthesia. [PDF]

Cureus
DeLeon A, Tureanu L, Vetter O, Liu T, Korula R, Garcia Tomas V, Asher Y.   +6 more
europepmc   +1 more source

Mechanical Tricuspid Valve Thrombosis Successfully Treated With Tissue Plasminogen Activator. [PDF]

JACC Case Rep
Haraf R, Atkinson T, Elizabeth Le DT, Arora B.   +3 more
europepmc   +1 more source

Diagnostic value of tissue plasminogen activator-inhibitor complex in sepsis-induced liver injury: A single-center retrospective case-control study. [PDF]

World J Hepatol
Zhou Y, He LP, Qi YH, Huang Y, Hu BQ, Liu JL, Zeng QB, Song JC.   +7 more
europepmc   +1 more source

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Tissue Plasminogen Activator

New England Journal of Medicine, 1988
TISSUE plasminogen activator (t-PA) is a naturally occurring protein that catalyzes the conversion of the inactive proenzyme plasminogen into the active serine protease plasmin.
John A. Oates, Alastair J.J. Wood, Joseph Loscalzo, Eugene Braunwald   +3 more
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Tissue Activator of Plasminogen

Nature, 1964
SINCE Astrup and Permin1 reported that animal tissue cells contain an activator of plasminogen, various authors have confirmed their results, and comparisons of the activator content of different human2 and animal tissues3,4 have been published. Most authors have used whole tissue or aqueous tissue extracts and have estimated activity by the fibrin ...
C H, LACK, S Y, ALI
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Tissue-Type Plasminogen Activator

Pathophysiology of Haemostasis and Thrombosis, 1986
Tissue-type plasminogen activator (t-PA) is a serine protease with a molecular weight of about 70,000. It activates plasminogen to plasmin by cleavage of the Arg 560-Val 561 peptide bond. Kinetic analysis showed that the activation obeys Michaelis-Menten kinetics and that the presence of fibrin strikingly enhances the activation rate.
H R, Lijnen, D, Collen
openaire   +2 more sources