Results 321 to 330 of about 282,486 (379)

Adding Tirofiban on Top of Recombinant Tissue Plasminogen Activator May Improve Clinical Outcome in Acute Stroke Patients. [PDF]

J Stroke
Liu R, Liang Z, Li W, Zhan Y, Xu L, Yang S, Zheng G, Jiang L, Xie L, Sun Z, Hu Y.   +10 more
europepmc   +1 more source

Dexmedetomidine Reduces Chronic Stress–Related Thrombosis in a Mouse FeCl3 Model

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Schematic summary of the mechanism by which dexmedetomidine prevents chronic stress–related carotid artery thrombosis in a mouse FeCl3 model. These findings present evidence and a potential mechanistic explanation of the Dex‐mediated amelioration of arterial thrombosis associated with the reduction of oxidative stress, inflammation, and apoptosis, and ...
Huazhen Wang, Meiping Zhang, Minglong Xin, Xueling Yue, Jinshun Piao, Longguo Zhao, Hehui Bi, Shiyan Wang, Chunzi Jin, Yongshan Nan, Xianglan Jin, Xian Wu Cheng   +11 more
wiley   +1 more source

The Holy Grail of cardiology?

Experimental Physiology, EarlyView.
Richard Godfrey
wiley   +1 more source

SNAP‐Tag–Based Recombinant Photoimmunotherapeutic Agents for the Selective Detection and Killing of Light‐Accessible Melanotransferrin‐Expressing Melanoma and Triple‐Negative Breast Cancer

Cancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background Melanoma and triple negative breast cancer (TNBC) represent the most aggressive skin and breast cancer subtypes and are associated with poor diagnostic and limited therapeutic options leading to poor prognosis. Melanotransferrin/p97 (MTf), initially identified as a tumor‐associated antigen (TAA) in melanoma, is overexpressed in ...
Suzanne Hippolite Magagoum, Fleury Augustin Nsole Biteghe, Gael Tchokomeni Siwe, Dirk Lang, Nkhasi Lekena, Stefan Barth   +5 more
wiley   +1 more source

Mediation of long-pulsed ultrasound enhanced microbubble recombinant tissue plasminogen activator thrombolysis in a rat model of platelet-rich thrombus. [PDF]

Cardiovasc Diagn Ther
Zhou S, Li J, Chen X, Huang B, Lu D, Zhang T.   +5 more
europepmc   +1 more source

Direct Oral Anticoagulants Are Comparable to Low Molecular Weight Heparin at Sustaining the Circulating Extracellular Vesicle and Inflammatory Profiles of Cancer Associated Thrombosis Patients: An Observational Pilot Study

Cancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Introduction Cancer patients face a 4 to 7‐fold higher risk of developing thrombotic events compared to individuals without cancer. This elevated risk is driven by the underlying tumour biology and the effects of cancer treatments, significantly increasing the mortality rates of these patients.
H. Macleod, N. Copty, D. Doherty, L. Weiss, E. Fouhy, R. Power, N. Ryan, K. Saeed, E. ORourke, R. Faryal, S. Kelliher, B. Kevane, F. Ní Áinle, P. B. Maguire   +13 more
wiley   +1 more source

Diffuse Multifocal Intracranial Hemorrhage Following Alteplase Infusion: A Case Image Report

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT Hemorrhage beyond the ischemic area is an uncommon but serious complication of thrombolysis. This case underscores the importance of timely recognition of atypical bleeding sites, careful monitoring, and strict blood pressure control to improve outcomes in ischemic stroke patients post‐thrombolysis.
Abdallah Alwali, Mohanad Faisal, Naveed Akhtar   +2 more
wiley   +1 more source

Unraveling the Serum Protein Landscape in Celiac Disease: Current Evidence and Future Directions

Immunity, Inflammation and Disease, Volume 13, Issue 5, May 2025.
Celiac disease (CD) is a chronic autoimmune disorder characterized by an abnormal immune response to gluten, leading to intestinal inflammation and various clinical manifestations. Transthyretin (TTR) is notably sensitive to nutritional status, serving as a potential marker of malabsorption.
Sajjad Bakhtiari, Behrooz Ahmadi, Nastaran Asri, Mostafa Rezaei‐Tavirani, Somayeh Jahani‐Sherafat, Andrea Masotti, Mohammad Rostami‐Nejad   +6 more
wiley   +1 more source

Role of Extracellular Vesicles in the Pathogenesis of Brain Metastasis

Journal of Extracellular Biology, Volume 4, Issue 5, May 2025.
ABSTRACT Extracellular vesicles (EVs) are small particles released by various cells, including cancer cells. They play a significant role in the development of different cancers, including brain metastasis. These EVs transport biomolecular materials such as RNA, DNA, and proteins from tumour cells to other cells, facilitating the spread of primary ...
Muhammad Izhar, Maciej S. Lesniak
wiley   +1 more source