Results 341 to 350 of about 282,486 (379)
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Tissue Plasminogen Activator and DNase in Empyema
New England Journal of Medicine, 2011Item does not contain ...
Simons, S.O. +2 more
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Studies on the kinetics of plasminogen activation by tissue plasminogen activator
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982The steady-state rate of plasminogen activation by tissue plasminogen activator has been determined at various plasminogen concentrations. A plasmin substrate method similar to that presented by Christensen and Müllertz (Biochim. Biophys. Acta 480 (1977) 257-281) was used.
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Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator
Thrombosis Research, 1990Here experimental evidence is presented demonstrating that Lp(a) inhibits the activation of Pg by the physiologic activator tissue-type plasminogen activator (t-PA) bound to fibrinogen fragments. The competitive inhibition constant, Kie, of the Lp(a) inhibition is 22 nM, or 8.6 mg/dL which corresponds to normal plasma ...
Jay M. Edelberg +2 more
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Kinetic studies of plasminogen activation by epithelial tissue plasminogen activator
Blood Coagulation & Fibrinolysis, 1990Initial-rate kinetic studies of the activation of plasminogen by epithelial activator were performed in the absence and in the presence of fibrinogen and CNBr-digested fibrinogen, under assay conditions similar to those described by Hoylaerts et al. (J Biol Chem, 257, 2912, 1982).
A Electricwala, R J Ling, Atkinson T
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Claims on tissue plasminogen activator
Nature, 1989A 'master' patent on a recombinant protein product has twice been overturned in British courts. The consequences may be far-reaching.
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Efficacy and safety of tissue plasminogen activator
Neurosurgery, 1987Simple aspiration to remove acute intracerebral hematomas has been thwarted by the solidity of the clot. Urokinase, a first generation fibrinolytic agent, has been used to liquefy such clots with some success. Therefore, tissue plasminogen activator (t-PA), a second generation fibrinolytic drug that may be safer and more effective, was studied to ...
David Bernstein +4 more
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Content of Tissue Activator of Plasminogen in Monkey Tissues
Thrombosis and Haemostasis, 1957SummaryThe content of the tissue activator of plasminogen in various organs from monkey is generally lower than in the corresponding human organs and approaches the concentration in the organs of other animals.
H. R Roberts, Tage Astrup
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Thrombosis Research, 1988
Glu-plasminogen (Glu-plg), Lys-plg and Val442-plg (mini-plg) were activated by urokinase (UK), streptokinase (SK) or tissue plasminogen activator (t-PA). Their activation rates were kinetically analyzed. UK activated Lys-plg with smaller Km and nearly identical Vmax as Glu-plg.
Yoshiaki Sugawara +2 more
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Glu-plasminogen (Glu-plg), Lys-plg and Val442-plg (mini-plg) were activated by urokinase (UK), streptokinase (SK) or tissue plasminogen activator (t-PA). Their activation rates were kinetically analyzed. UK activated Lys-plg with smaller Km and nearly identical Vmax as Glu-plg.
Yoshiaki Sugawara +2 more
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Radiation therapy‐associated toxicity: Etiology, management, and prevention
Ca-A Cancer Journal for Clinicians, 2021Kyle Wang
exaly