Results 61 to 70 of about 599,368 (371)
Low‐field MRI: Clinical promise and challenges
Journal of Magnetic Resonance Imaging, Volume 57, Issue 1, Page 25-44, January 2023., 2023 Modern MRI scanners have trended toward higher field strengths to maximize signal and resolution while minimizing scan time. However, high‐field devices remain expensive to install and operate, making them scarce outside of high‐income countries and major population centers.
Thomas Campbell Arnold +3 more
wiley +1 more source
Estimating the Roles of Protonation and Electronic Polarization in Absolute Binding Affinity Simulations [PDF]
arXiv, 2021 Accurate prediction of binding free energies is critical to streamlining the drug development and protein design process. With the advent of GPU acceleration, absolute alchemical methods, which simulate the removal of ligand electrostatics and van der Waals interactions with the protein, have become routinely accessible and provide a physically ...
arxiv
Predicting multicellular function through multi-layer tissue networks [PDF]
Bioinformatics 2017, 33 (14): i190-i198, 2017 Motivation: Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cellular function remains a critical challenge for biomedicine. Results: Here we present OhmNet, a hierarchy-aware unsupervised node feature learning approach for multi-layer ...
arxiv +1 more source
Vertex model instabilities for tissues subject to cellular activity or applied stresses [PDF]
Phys. Rev. E 102, 052604 (2020), 2020 The vertex model is widely used to describe the dynamics of epithelial tissues, because of its simplicity and versatility and the direct inclusion of biophysical parameters. Here, it is shown that quite generally, when cells modify their equilibrium perimeter due to their activity, or the tissue is subject to external stresses, the tissue becomes ...
arxiv +1 more source
Plasminogen influence on the PAI-1 release by human platelets [PDF]
The Ukrainian Biochemical JournalРАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova +3 more
doaj +1 more source
Enablers of the implementation of tissue plasminogen activator in acute stroke care: a cross-sectional survey. [PDF]
PLoS ONE, 2014 To assess emergency physicians' perceptions of individual and system enablers to the use of tissue Plasminogen Activator in acute stroke.Australian fellows and trainees of Australasian College for Emergency Medicine completed a 57-item online survey ...
Alice Grady +4 more
doaj +1 more source
Immunological analysis of plasminogen activators from normal and transformed hamster cells... [PDF]
, 1975 Rabbits were immunized against the plasminogen activator released by SV4- virus-transformed hamster embryo cells. The resulting antiplasminogen activator immunoglobulin (APA-IgG) inhibited the enzymatic activity of the plasminogen activator produced by ...
Acs, George +2 more
core +2 more sources
Lung India, 2022 Severe hypoxia due to coronavirus disease 2019 (COVID-19) is challenging in the intensive care unit (ICU). It is often unresponsive to mechanical ventilation at high positive end-expiratory pressure and the fraction of inspired oxygen combination.
Zia Hashim +3 more
doaj +1 more source
Induction in myeloid leukemic cells of genes that are expressed in different normal tissues [PDF]
PNAS 101, 16022 (2004), 2005 Using DNA microarray and cluster analysis of expressed genes in a cloned line (M1-t-p53) of myeloid leukemic cells, we have analyzed the expression of genes that are preferentially expressed in different normal tissues. Clustering of 547 highly expressed genes in these leukemic cells showed 38 genes preferentially expressed in normal hematopoietic ...
arxiv +1 more source
Shock, 2014 Severe hyperfibrinolysis after trauma is a poorly understood phenomenon associated with profound shock, serious anatomic injuries, increased transfusions, and high mortality rates.
J. Cardenas +5 more
semanticscholar +1 more source