Results 51 to 60 of about 1,163,814 (206)

Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration

open access: yesMilitary Medical Research
Scar formation resulting from burns or severe trauma can significantly compromise the structural integrity of skin and lead to permanent loss of skin appendages, ultimately impairing its normal physiological function.
Ying-Ying Li   +4 more
doaj   +1 more source

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes [PDF]

open access: yes, 2020
Fibroblast growth factors (FGFs) are key regulators of tissue development, homeostasis and repair, and abnormal FGF signalling is associated with various human diseases.
Ben-Yehuda Greenwald, Maya   +9 more
core   +2 more sources

Biomaterials for tissue repair [PDF]

open access: yesScience, 2019
Biomaterials can promote endogenous healing without delivering cells or ...
openaire   +2 more sources

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]

open access: yes, 2007
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit   +6 more
core   +1 more source

Eicosanoids in tissue repair [PDF]

open access: yesImmunology & Cell Biology, 2019
AbstractTrauma or infection can result in tissue damage, which needs to be repaired in a well‐orchestrated manner to restore tissue function and homeostasis. Lipid mediators derived from arachidonic acid (termed eicosanoids) play central and versatile roles in the regulation of tissue repair. Here, I summarize the current state‐of the‐art regarding the
openaire   +3 more sources

Effects of exosomes derived from placental mesenchymal stem cells on high glucose-induced senescence in human dermal fibroblasts

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the optimal conditions for inducing senescence in human dermal fibroblasts (HDFs) cultured in high glucose and observe the effect of exosomes derived from human placental mesenchymal stem cells (PMSCs) on the proliferation, migration
BIAN Xiaowei   +6 more
doaj   +1 more source

Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes

open access: yesBone & Joint Research, 2023
Aims: To explore the novel molecular mechanisms of histone deacetylase 4 (HDAC4) in chondrocytes via RNA sequencing (RNA-seq) analysis. Methods: Empty adenovirus (EP) and a HDAC4 overexpression adenovirus were transfected into cultured human chondrocytes.
Li Guo   +9 more
doaj   +1 more source

BMN673 sensitizes rhabdomyosarcoma tumors to irradiation in vivo [PDF]

open access: yes, 2020
Bone and soft tissue sarcomas are mesenchymal tumors that occur rarely in adults, representing only 1% of total malignancies, but comprise up to 13% of malignant tumors in children.1 Rhabdomyosarcoma, a soft tissue sarcoma that commonly affects children,
Jacob, Connor
core  

PTX3 orchestrates tissue repair

open access: yesOncotarget, 2015
Innate immunity is the first line of resistance against pathogens, but it has also an important role in maintaining tissue homeostasis by regulating inflammatory and repair responses after tissue injury [1]. Innate immunity consists of a cellular and humoral arm [1, 2]. It has been clearly established that cell-associated pattern-recognition molecules (
Andrea, Doni   +2 more
openaire   +2 more sources

Protein hydrolysates and tissue repair [PDF]

open access: yesNutrition Research Reviews, 2011
Protein hydrolysates provide a rich source of protein which is useful in situations where excess protein is needed, such as during repair of tissue damage. The consumption of protein hydrolysates has been shown to result in more rapid uptake of amino acids compared with whole proteins or free-form amino acid mixtures and some peptides in hydrolysates ...
Rebecca L, Thomson, Jonathan D, Buckley
openaire   +3 more sources

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