Results 81 to 90 of about 1,163,814 (206)
Nature CommunicationsChronic wounds are a major complication in patients with diabetes. Here, we identify a therapeutic circRNA and load it into small extracellular vesicles (sEVs) to treat diabetic wounds in preclinical models.
Qilin Huang +14 more
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Advances and applications of biomimetic biomaterials for endogenous skin regeneration
Bioactive MaterialsEndogenous regeneration is becoming an increasingly important strategy for wound healing as it facilitates skin's own regenerative potential for self-healing, thereby avoiding the risks of immune rejection and exogenous infection.
Mengyang Wang +3 more
doaj +1 more source
A Current Overview of Materials and Strategies for Potential Use in Maxillofacial Tissue Regeneration [PDF]
, 2017 Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The production of biodegradable, customizable scaffolds to achieve this clinical aim is dependent on the interdisciplinary collaboration among clinicians, bioengineers ...
Almeida, Luis Eduardo +7 more
core +1 more source
Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling. [PDF]
, 2020 Organisms respond to tissue damage through the upregulation of protective responses which restore tissue structure and metabolic function. Mitochondria are key sources of intracellular oxidative metabolic signals that maintain cellular homeostasis.
Chisholm, Andrew D +9 more
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Cell Transplantation, 2003 Hepatocyte-based therapy has been proposed as an alternative to organ transplantation in the treatment of liver disorders. In the clinical context, a major issue is the constant supply of quality assurance-controlled hepatocytes, thereby requiring their ...
Stephan Mahler +6 more
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Sequential Wnt Agonist then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis [PDF]
, 2019 Tissue fibrosis compromises organ function and occurs as a potential long-term outcome in response to acute tissue injuries. Currently, lack of mechanistic understanding prevents effective prevention and treatment of the progression from acute injury to ...
Fu, Haiyan +7 more
core +2 more sources
Human urinary cells for functional wound healing with sweat gland restoration
Military Medical Research, 2023 Shuai-Fei Ji +7 more
doaj +1 more source
Bioactive materials for in vivo sweat gland regeneration
Bioactive MaterialsLoss of sweat glands (SwGs) commonly associated with extensive skin defects is a leading cause of hyperthermia and heat stroke. In vivo tissue engineering possesses the potential to take use of the body natural ability to regenerate SwGs, making it more ...
Xinling Yang +3 more
doaj +1 more source
, 2011 Mesenchymal stem cells are multipotent stromal cells residing within the connective tissue of most organs. Their surface phenotype has been well described.
Grange, Simon
core
Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration
Cell Communication and SignalingAutophagy is a self-renewal mechanism that maintains homeostasis and can promote tissue regeneration by regulating inflammation, reducing oxidative stress and promoting cell differentiation.
Yan Wu +8 more
doaj +1 more source