Results 51 to 60 of about 263,916 (334)

Whole-Heart Tissue Engineering and Cardiac Patches: Challenges and Promises

Bioengineering, 2023
Despite all the advances in preventing, diagnosing, and treating cardiovascular disorders, they still account for a significant part of mortality and morbidity worldwide.
Aram Akbarzadeh, Soheila Sobhani, Alireza Soltani Khaboushan, Abdol-Mohammad Kajbafzadeh   +3 more
doaj   +1 more source

Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan [PDF]

, 2012
A novel modeling technique for porous tissue scaffolds with targeting the functionally gradient variational porosity with continuous material deposition planning has been proposed.
Khoda, AKM B., Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +4 more
core   +1 more source

Transforming layered 2D mats into multiphasic 3D nanofiber scaffolds with tailored gradient features for tissue regeneration

BMEMat
Multiphasic scaffolds with tailored gradient features hold significant promise for tissue regeneration applications. Herein, this work reports the transformation of two‐dimensional (2D) layered fiber mats into three‐dimensional (3D) multiphasic scaffolds
S. M. Shatil Shahriar, Navatha Shree Polavoram, Syed Muntazir Andrabi, Yajuan Su, Donghee Lee, Huy Quang Tran, Samantha J. Schindler, Jingwei Xie   +7 more
doaj   +1 more source

Nanotechnology Biomimetic Cartilage Regenerative Scaffolds

Archives of Plastic Surgery, 2014
Cartilage has a limited regenerative capacity. Faced with the clinical challenge of reconstruction of cartilage defects, the field of cartilage engineering has evolved. This article reviews current concepts and strategies in cartilage engineering with an
Erh-Hsuin Lim, Jose Paulo Sardinha, Simon Myers   +2 more
doaj   +1 more source

Recent advances in 3D printing of biomaterials. [PDF]

, 2015
3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. [PDF]

, 2015
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity.
Beegle, Julie R, Chávez, Myra N, Egaña, José T, Fierro, Fernando A, Isseroff, Roslyn R, O'Neal, Adam J, Peavy, Thomas R   +6 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Three-dimensional analysis of micro- and nanostructure of biomaterials and cells by method of scanning probe nanotomography

Вестник трансплантологии и искусственных органов, 2018
Aim: to perform a three-dimensional analysis of micro- and nanosctucture and quantitative morphological parameters of alginate spherical microcarriers and porous regenerated silk macrocarriers modifi ed by microparticles of decellularized rat liver matrix
A. E. Efimov, O. I. Agapova, L. A. Safonova, M. M. Bobrova, I. I. Agapov   +4 more
doaj   +1 more source

A mechanistic approach to design smart scaffolds for tissue engineering [PDF]

, 2006
This thesis describes a library of novel 3D scaffolds designed and optimized for tissue engineering and regenerative medicine applications. Tissue engineering aims at restoring or regenerating a deamaged tissue by combining cells, derived from a patient ...
Moroni, Lorenzo
core   +1 more source