Freeform Fabrication of Biological Scaffolds by Projection Photopolymerization [PDF]
This article presents a micro-manufacturing method for direct, projection printing of 3- dimensional (3D) scaffolds for applications in the field of tissue engineering by using a digital micro-mirror-array device (DMD) in a layer-by-layer process ...
Chen, Shaochen +3 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Designing bio-mimetic variational porosity for tissue scaffolds [PDF]
Reconstructing or repairing the damaged or diseased tissues with porous scaffolds to restore the mechanical, biological and chemical functions is one of the major tissue engineering strategies.
Khoda, AKM +2 more
core
Automated Design of Tissue Engineering Scaffolds by Advanced CAD [PDF]
The design of scaffolds with an intricate and controlled internal structure represents a challenge for Tissue Engineering. Several scaffold manufacturing techniques allow the creation of complex and random architectures, but have little or no control ...
Harris, R. A., Ramin, E.
core +1 more source
Nanofiber Structured Polymeric Tissue Scaffolds
Tissue scaffolds are 3D, porous, biodegradable, and biocompatible materials which have an appropriate mechanical strength. Tissue scaffolds enable attachment, proliferation, and differentiation of seeded cultured cells on them. These cells form a tissue by connecting to each other. Electrospinning is one of the most preferred methods in nanospun tissue
CAN, Nilay, ERSOY, Mehmet
openaire +2 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Commentary: benefits and challenges of cellularized scaffolds for treatment of volumetric muscle loss [PDF]
Bulk local tissue loss may be amenable to scaffold based therapies. Discrete areas can usually be filled in with composite scaffolds, which can then conform and integrate to host tissue.
Indranil Sinha, Ali Tamayol
doaj +1 more source
3D printing of bone tissue engineering scaffolds
Tissue engineering is promising in realizing successful treatments of human body tissue loss that current methods cannot treat well or achieve satisfactory clinical outcomes.
Chong Wang +11 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration
Scaffold‐based tissue engineering provides an efficient approach for repairing uterine tissue defects and restoring fertility. In the current study, a novel trilayer tissue engineering scaffold with high similarity to the uterine tissue in structure was ...
Shangsi Chen +4 more
doaj +1 more source

