Results 91 to 100 of about 1,964,988 (291)
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Biomaterial scaffolds for tissue engineering
Reconstruction and regeneration of new tissues are challenges facing scientists, technologists and clinicians. This review describes strategies of selection and design of biomaterials having significant impact on various possible synthesis routes for scaffold fabrication.
Kajal K, Mallick, Sophie C, Cox
openaire +2 more sources
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Dermal regenerative matrices (DRMs) are extracellular matrix–based biomaterials designed to provide structural support and promote site-appropriate tissue regeneration; acellular dermal matrices (ADMs) represent the most widely used clinical subtype of ...
Mohd. Altaf Mir +6 more
doaj +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Bioactive glass and glass-ceramic scaffolds for bone tissue engineering [PDF]
Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone tissue engineering applications.
Boccaccini, A.R. +8 more
core +2 more sources
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Novel processing of porous bioceramic structures [PDF]
Bone is one of the most commonly replaced tissues in the body. Bone tissue engineering has become one of the key areas of research as a successful treatment option for bone regeneration.
Muthutantri, A.I., Muthutantri, A I
core
An explicit constitutive reconstruction framework enables accurate tensile characterization of miniaturized additively manufactured specimens using only the grip‐to‐grip displacement measurements. Progressive validation through self‐consistency, analytical comparison, and inverse finite element method (iFEM) benchmarking demonstrates constitutive ...
Junqing Leng +4 more
wiley +1 more source
Integrated onto three-dimensional (3D) scaffolds, graphene quantum dots (GQDs) present a novel method for tissue creation and precision drug delivery. Among its special characteristics are photoluminescence, biocompatibility, and a large surface area fit
Yuvaraj Muthu +4 more
doaj +1 more source

