Layered Fabrication of Branched Networks Using Lindenmayer Systems [PDF]
, 2007 A current challenge impeding the growth of bone tissue engineering is the lack of functional scaffolds of geometric sizes greater than 10mm due to the inability of cells to survive deep within the scaffold.
Harris, C. +4 more
core +1 more source
Biomaterial scaffolds for tissue engineering
Frontiers in Bioscience, 2013 Reconstruction and regeneration of new tissues are challenges facing scientists, technologists and clinicians. This review describes strategies of selection and design of biomaterials having significant impact on various possible synthesis routes for scaffold fabrication.
Kajal K, Mallick, Sophie C, Cox
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Chitosan/hydroxyapatite scaffolds for tissue engineering manufacturing method effect comparison
Revista Facultad de Ingeniería Universidad de Antioquia, 2015 The regeneration of bone is one of the main challenges of modern medicine because many diseases including trauma and tumor can cause bone defects.
Diana Marcela Escobar-Sierra +2 more
doaj +1 more source
A 3-D in vitro co-culture model of mammary gland involution. [PDF]
, 2014 Involution is a process whereby the mammary gland undergoes extensive tissue remodelling involving exquisitely coordinated cell death, extracellular matrix degradation and adipose tissue regeneration following the weaning of offspring.
Botos, Laur-Alexandru +5 more
core +3 more sources
Insight into the interaction of pluronic F‐127 functionalized boron nitride nanosheets with piezoelectric poly(
, 2023 Madeshwaran Sekkarapatti Ramasamy +9 more
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Photothermal nanomaterials-based scaffolds for tissue regeneration and cancer therapy
Medicine in Novel Technology and DevicesRecently, photothermal therapy (PTT) has been considered a promising method for cancer treatment with fewer serious side effects compared to conventional radiation, chemotherapy and surgical resection.
Kuldeep Rajpoot
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Bioactive composites for bone tissue engineering [PDF]
, 2010 One of the major challenges of bone tissue engineering is the production of a suitable scaffold material. In this review the current composite materials options available are considered covering both the methods of both production and assessing the ...
Tanner, K.E.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source