Results 71 to 80 of about 421,672 (303)

Engineering contractile myocardial tissue using extracellular matrix scaffolds [PDF]

, 2013
There is currently an overwhelming need for functional replacement of diseased or damaged cardiac tissue. Biologic based scaffolds are an attractive tissue engineering approach to cardiac repair because they avoid sensitization associated with homograft ...
Remlinger, Nathaniel
core  

The immunological relationship between filtrable agent, Salmonella and murine leukosis

, 1977
Salmonella typhimurium was invariably isolated from our J strain murine leukosis. Immunization of D103 mice with either inactivated Salmonella typhimurium or the cell-free extract of leukosis inhibited the transplantation of leukosis.
Hamazaki, Yukio
core   +1 more source

Efficacy of consolidation high-dose chemotherapy with ifosfamide, carboplatin and etoposide (HD-ICE) followed by autologous peripheral blood stem cell rescue in chemosensitive patients with metastatic soft tissue sarcomas [PDF]

, 2006
Background: Prognosis of patients with metastatic soft tissue sarcomas (MSTS) is poor even after response to doxorubicin-based chemotherapy. We report phase II data of highdose chemotherapy and peripheral blood stem cell (PBSC) rescue in patients with ...
Hentrich, M., Licht, Thomas, Straka, Christian, Rolf-Dieter Issels, Wendtner, Clemens-Martin, Marcus Schlemmer, Hiddemann, Wolfgang, Abdel-Rahman, Sultan, Sultan Abdel-Rahman, Issels, Rolf-Dieter, Salat, C., Baumert, Jens, Straka, C., Hiddemann, W., Falk, Martin, Issels, R.D., Wolfgang Hiddemann, Martin Falk, Jens Baumert, Falk, M., Thomas Licht, Schlemmer, M., Marcus Hentrich, Licht, T., Salat, Christoph, Christoph Salat, Abdel-Rahman, S., Clemens-Martin Wendtner, Schlemmer, Marcus, Wendtner, C.M., Baumert, J.J., Hentrich, Marcus, Christian Straka   +32 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]

, 2009
We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I, Arnaud Scherberich, Montjovent, MO, Scherberich, A, Scherberich, Arnaud, Lee Ann Applegate, Montjovent, Marc-Olivier, Marc-Olivier Montjovent, Scaletta, Corinne, Dominique P. Pioletti, Bocelli-Tyndall, Chiara, Martin, Ivan, Applegate, LA, Laurent-Applegate, Lee, Bocelli-Tyndall, C., Pioletti, DP, Scherberich, A., Silke Mark, Montjovent, M.O., Scaletta, C, Pioletti, Dominique P., Mark, Silke, Mark, S., Bocelli-Tyndall, C, Applegate, Lee Ann, Mark, S, Pioletti, D.P., Corinne Scaletta, Scaletta, C., Ivan Martin, Martin, I., Applegate, L.A., Chiara Bocelli-Tyndall   +32 more
core   +1 more source

Pigmented melanoma cell migration study on murine syngeneic B16F10 melanoma cells or tissue transplantation models

Journal of Mind and Medical Sciences, 2019
Melanoma is a lethal form of skin cancer with poor prognosis, especially due to the early metastatic feature. Recent studies have shown that the melanin pigment influences the nanomechanical properties and, therefore, the metastatic behavior of the ...
Maria-Cristina Predoi, Ion Mîndrilă, Sandra Alice Buteică, Ovidiu Marcel Mărginean, Bogdan Mîndrilă, Mihaela Niculescu   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Composite Tissue Allotransplantation: Hand Transplantation and Beyond

, 2010
Recent advances in transplant immunology are shifting the focus from immunosuppression to immunoregulation, making composite tissue allotransplantation with novel and less potent immunosuppressive regimens a possibility. Hand transplantation has been the
Lee, W.P. Andrew, Gorantla, Vijay S., Brandacher, Gerald, Schneeberger, Stefan, Shores, Jaimie T.   +4 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation

, 2013
The lung is, more than other solid organs, susceptible for ischemia reperfusion injury after orthotopic transplantation. Corticosteroids are known to potently suppress pro-inflammatory processes when given in the post-operative setting or during ...
Haitham Mutlak, Paulus, Patrick, Mutlak, Haitham, Johannes Holfeld, Haitham Mutlak (452006), Sabine Tacke (318720), David Stay (452009), Patrick Paulus, Holfeld, Johannes, Urbschat, Anja, Christin Reissig, Pia Alexandra Ockelmann, Reissig, Christin, Zacharowski, Kai, Tacke, Sabine, Bertram Scheller (318724), Stay, David, Bertram Scheller, Ockelmann, Pia Alexandra, Scheller, Bertram, Kai Zacharowski (77285), Sabine Tacke, Johannes Holfeld (318725), Patrick Paulus (318716), Anja Urbschat, Kai Zacharowski, Christin Reissig (452008), Anja Urbschat (318726), David Stay, Pia Alexandra Ockelmann (452007)   +29 more
core   +1 more source