Results 51 to 60 of about 2,522,129 (303)

Human tissue legislation in the United Kingdom 1952- 2006: a history and comparative analysis of policy development [PDF]

, 2011
PhDThis is a study of the genesis of the Corneal (Grafting) Act 1952, the Human Tissue Act 1961, the Human Tissue Act 2004, and the Human Tissue (Scotland) Act 2006.
McNeish, Alexander Stewart
core   +4 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Influence of Pharmacological Preconditioning with Sevoflurane on Incidence of Early Allograft Dysfunction in Liver Transplant Recipients

Anesthesiology Research and Practice, 2012
Background. Pharmacological preconditioning is one of the tools used to diminish preservation injury. We investigated the influence of sevoflurane preconditioning of liver grafts on postoperative graft function. Methods.
Andrei F. Minou, Alexander M. Dzyadzko, Aliaksei E. Shcherba, Oleg O. Rummo   +3 more
doaj   +1 more source

Generation of bioartificial hearts using decellularized scaffolds and mixed cells

BioMedical Engineering OnLine, 2019
Background Patients with end-stage heart failure must receive treatment to recover cardiac function, and the current primary therapy, heart transplantation, is plagued by the limited supply of donor hearts.
Cailing Tong, Cheng Li, Baiyi Xie, Minghui Li, Xianguo Li, Zhongquan Qi, Junjie Xia   +6 more
doaj   +1 more source

Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis

Journal of Neuroinflammation, 2020
Background Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system characterized by severe white matter demyelination. Because of its complex pathogenesis, there is no definite cure for MS.
Ke An, Meng-Jiao Xue, Jia-Ying Zhong, Sheng-Nan Yu, Tian-Shu Lan, Zhong-Quan Qi, Jun-Jie Xia   +6 more
doaj   +1 more source

Long non‐coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer

Clinical and Translational Medicine, 2022
Background Gastric cancer (GC) is one of the most common types of cancer worldwide, which leads to more than 10% of cancer‐related deaths. Metabolism reprogramming presents as a pivotal event in cancer initiation and progression through enhancing aerobic
Ting Dai, Xin Zhang, Xiang Zhou, Xiaoxia Hu, Xiaodi Huang, Feiyue Xing, Han Tian, Yun Li   +7 more
doaj   +1 more source

Improving self-sufficiency in organ transplantation in Korea [PDF]

, 2021
After attaining a qualified medical capacity in organ transplantation, Korea has been struggling to increase the number of deceased organ transplants to reach self-sufficiency.
김명수, 김순일
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Eligible DBD Donors Proceeding via the DCD Pathway: Incidence, Cause, and Outcomes in the United Kingdom

Transplantation Direct
Background. Eligible donation after brain death (DBD) donors may rarely proceed via the donation after circulatory death (DCD) pathway. The incidence, reasons for pathway divergence, and graft and recipient outcomes in the United Kingdom of this cohort ...
Mark Burgess, MBChB, MSc, FRCA, FFICM, MRCP, Laura Silsby, BSc, Susanna Madden, MSc, Joana Da Silva Letra, RN, Stephanie Thomson, Diploma in Nursing, Janine Tate, BSc, Diploma in Intensive Care, Sharon Mitchinson, Diploma in Nursing, Katherine Hurley, BSc, Rebecca Hurley, BSc, Marco Bon, Diploma in Nursing, Rachel Pritchard, BSc, Sue Duncalf, BSc, Dale Gardiner, MBBS, MBioEth, FFICM   +12 more
doaj   +1 more source

The use of cadaver tissues in transplantation

Transplantation, 1964
IN the short span of thirteen years human-kidney homotransplantation has progressed from developmental uncertainty to a therapeutic endeavor that has rehabilitated many patients in terminal renal failure, both in this country and abroad. Contrary to many apprehensions, the use of drugs to suppress the immune response to homografts has not been ...
N P, COUCH, W J, CURRAN, F D, MOORE
openaire   +3 more sources