Results 101 to 110 of about 436,080 (341)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

Advanced Science
The industrial microbial production of fatty acids is limited by low titers and productivities, highlighting the need for chassis engineering and mechanistic insights into efficient metabolic pathways.
Fangzhong Wang, Weijia Jin, Tiantian Wang, Junkai Ji, Kun Cao, Jianqiang Li, Lei Chen, Weiwen Zhang   +7 more
doaj   +1 more source

Association of Tissue Transglutaminase Antibody Titer with Duodenal Histological Changes in Children with Celiac Disease

Gastroenterology Research and Practice, 2016
Celiac disease is usually diagnosed by demonstrating gluten enteropathy in small bowel biopsy. Celiac specific antibodies are used as an initial screening test.
Hasan Hawamdeh, Basim Al-Zoubi, Yasameen Al Sharqi, Ayman Qasrawi, Yousef Abdelaziz, Maha Barbar   +5 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Factors Associated with SARS-CoV-2 Antibody Titer After Sinovac Vaccination Among Health Care Workers

Acta Medica Indonesiana, 2022
Background: One of the methods to record immunogenicity after vaccination is to measure antibody titer. This study aimed to get the value of antibody titer post Sinovac vaccination and to analyze factors that associate with it. The trend of titer changes
Theresia Santi, Baringin De Samakto, Lina Kamarga, Feronica Kusuma Hidayat, Ferry Hidayat   +4 more
doaj   +2 more sources

Association between hypogonadism and reproductive tissue steroid-producing cells antibody in men with positive MAR test IgG and diabetes mellitus type 1

Сахарный диабет, 2019
BACKGROUND: Autoimmune hypogonadism is frequently taped in men with positive direct mixed agglutination reaction antisperm antibodies IgG test (MAR test IgG).
Roman V. Rozhivanov, Irina I. Vitiazeva
doaj   +1 more source

Pneumococcal Antibody Titers

Global Pediatric Health, 2017
Purpose: Immunoglobulin replacement is the mainstay treatment in patients with humoral immunodeficiencies, yet a handful of patients continue to develop sinopulmonary infections while on therapy. The objective of our study was to compare immunoglobulin G (IgG) pneumococcal antibody levels in patients with humoral immune deficiencies who have been on ...
Pamella F. Abghari MD, Pavadee Poowuttikul MD, Elizabeth Secord MD, FAAAAI   +2 more
openaire   +1 more source

Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides. [PDF]

, 2020
BACKGROUND:Rhodosporidium toruloides has emerged as a promising host for the production of bioproducts from lignocellulose, in part due to its ability to grow on lignocellulosic feedstocks, tolerate growth inhibitors, and co-utilize sugars and lignin ...
Burnum-Johnson, Kristin E, Clay, Derek M, Gao, Yuqian, Geiselman, Gina M, Gladden, John M, Kirby, James, Magnuson, Jon K, Munoz Munoz, Nathalie, Nicora, Carrie D, Papa, Gabriella, Prahl, Jan-Philip, Skerker, Jeffrey M, Sundstrom, Eric R, Tanjore, Deepti, Tran-Gyamfi, Mary B, Zhuang, Xun   +15 more
core   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

High-titer packaging cells producing recombinant retroviruses resistant to human serum [PDF]

, 1995
François–Loïc Cosset, Yasuhiro Takeuchi, Jean‐Luc Battini, Robin A. Weiss, Mary Collins   +4 more
openalex   +1 more source