Results 121 to 130 of about 445,796 (343)
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen+30 more
wiley +1 more source
An Improved Serologic Method for the Determination of the Precipitative Titers of Antisera [PDF]
Paul R. Cannon, Charles E. Marshall
openalex +1 more source
Fibrinolytic Titer of Scarlatinal Streptococci.
Applying the Tillett-Garner plasma-clot technic1 with rate of thrombolysis as the quantitative index, Dack, Woolpert and Hoyne2 found a slight correlation between thrombolytic titer and clinical severity of scarlet fever. At the time of the publication of their paper a similar study of scarlatinal streptococci was in progress in our laboratories We had
R. R. Madison, Frieda H. Fraser
openaire +2 more sources
A scalable one‐step copolymerization strategy is developed to produce low‐cost microporous ion exchange membranes that boost both the efficiency and lifespan of flow batteries. When combined with organic electrolytes in aqueous systems, these membranes enable safe and cheap flow battery energy storage, supporting the widespread integration of renewable
Jiaye Liu+7 more
wiley +1 more source
GROUP A HEMOLYTIC STREPTOCOCCUS ANTIBODIES. I. GRIFFITH TYPE AGGLUTININ AND ANTISTREPTOLYSIN TITERS IN NORMAL MEN AND IN ACUTE INFECTIONS [PDF]
Lowell A. Rantz+2 more
openalex +1 more source
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang+14 more
wiley +1 more source
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source
The Effect of a Malaria Infection on the Titer of Complement and its Components in Ducks [PDF]
Robert B. McGhee
openalex +1 more source
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain+5 more
wiley +1 more source