Results 171 to 180 of about 638,613 (387)
Production of high-titer helper-free retroviruses by transient transfection.
Proceedings of the National Academy of Sciences of the United States of America, 1993 Warren S. Pear +3 more
semanticscholar +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
LOW TITERS IN DROSOPHILA THAT REGULARLY TRANSMIT THE SIGMA VIRUS INFECTION [PDF]
, 1966 Robert L. Seecof
openalex +1 more source
Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity.
Journal of Infectious Diseases, 2000 D. Vaughn +10 more
semanticscholar +1 more source
CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis
Advanced Science, EarlyView.Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou +5 more
wiley +1 more source
On the Tits-Weiss Conjecture and the Kneser-Tits Conjecture for $\mathrm{E}^{78}_{7,1}$ and $\mathrm{E}^{78}_{8,2}$ [PDF]
, 2019 Seidon Alsaody +2 more
openalex +1 more source
Advanced Science, EarlyView.A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun +23 more
wiley +1 more source
Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons
Advanced Science, EarlyView.Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang +14 more
wiley +1 more source
Indonesia Medicus Veterinus, 2018 Penelitian ini bertujuan untuk mengetahui respon imun sekunder pascavaksinasi kedua AI pada peternakan komersial di Desa Denbantas, Kecamatan Tabanan. Sampel penelitian dipilih secara acak terhadap 10 ekor ayam petelur dari total 200 ekor. Sampel diambil
Zatya Wira Bhakty +2 more
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