Results 171 to 180 of about 438,789 (339)
Description of the Winiam Tit-Warbler, Acanthiza winiamida, sp. Nov.
Frank E. Wilson
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EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
The impact of pathogen reduction on ABO isoagglutinin titers in apheresis platelets. [PDF]
Yeghiazaryan M+5 more
europepmc +1 more source
Optimum Conditions for the Assay of Hemolytic Complement Titer of Carp and Seasonal Variation of the Titers [PDF]
Tomoki Yano, Miki Nakao, Hiroko Ando
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High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti+3 more
wiley +1 more source
Perfusion process with tangential flow filtration for oncolytic VSV-GP production. [PDF]
Hamusics O+7 more
europepmc +1 more source
High‐Throughput MicroED for Probing Ion Channel Dynamics
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito+4 more
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Bayesian optimization and machine learning for vaccine formulation development. [PDF]
Li L+5 more
europepmc +1 more source
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz+24 more
wiley +1 more source