Results 191 to 200 of about 638,613 (387)
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
The impact of repeated freeze-thaw cycles on antiphospholipid antibody titer [PDF]
Devreese, Katrien, Maelegheer, Karel
core +1 more source
Quantification of rose rosette emaravirus (RRV) titers in eriophyoid mites: insights into viral dynamics and vector competency [PDF]
Tobiasz Druciarek +2 more
openalex +1 more source
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang +8 more
wiley +1 more source
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
Consistent Detection of Aquaporin-4 Antibodies: A Comparative Analysis Between Fixed and Live Cell-Based Assays. [PDF]
Wang J +16 more
europepmc +1 more source

