Results 211 to 220 of about 438,789 (339)

Preparation and Storage of High-Titer Lactic Streptococcus Bacteriophages1 [PDF]

open access: gold, 1974
J. Nyiendo   +3 more
openalex   +1 more source

Antiviral effects and mechanism of Qi pi pill against influenza viruses

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang   +10 more
wiley   +1 more source

Multiple and Alternative Sites Make Tau Protein an Adaptable Sticky Surface for the SH3 Domain of Fyn Kinase

open access: yesAngewandte Chemie, EarlyView.
An NMR‐based study, combined with computational, calorimetric and in‐cell FRET methods, sheds light on the complex recognition mechanism between the intrinsically disordered protein Tau and the SH3 domain of Fyn kinase, highlighting how the multiple binding sites present in Tau make the protein an adaptable recognition surface that can function even ...
Roberto Tira   +8 more
wiley   +2 more sources

Green‐to‐red spectral labeling: A novel polysynaptic retrograde tracing strategy in the marker footprint mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song   +4 more
wiley   +1 more source

Supramolecular Recognition of a DNA Four‐Way Junction by an M2L4 Metallo‐Cage, Inspired by a Simulation‐Guided Design Approach

open access: yesAngewandte Chemie, EarlyView.
DNA Holliday junctions, or four‐way junctions (4WJs) are an attractive therapeutic target due to their prevalence in DNA replication and repair, and viral disease. Combining experimental and computational methods, we show that quadruple‐stranded dinuclear platinum metallo‐cages are an excellent size and shape match for the cavity of the 4WJ open ...
Samuel J. Dettmer   +6 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy