Results 21 to 30 of about 438,789 (339)

The use of low‐titer group O whole blood is independently associated with improved survival compared to component therapy in adults with severe traumatic hemorrhage

Transfusion, 2020
There is a resurgence in the use of low‐titer group O whole blood (LTOWB) for hemorrhagic shock. We hypothesized the use of LTOWB compared to component therapy (CT) would be independently associated with improved 24‐hour mortality.
Susan M. Shea, Amanda M. Staudt, Kimberly A. Thomas, Douglas J. E. Schuerer, J. E. Mielke, Danielle Folkerts, Ethan Lowder, Callista Martin, G. Bochicchio, P. Spinella   +9 more
semanticscholar   +1 more source

Immune Responses to SARS-CoV-2 Infection and Vaccination in Dialysis Patients and Kidney Transplant Recipients

Microorganisms, 2021
Dialysis patients and kidney transplant (KTX) recipients suffer from an impaired immune system and show a decreased response to the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) vaccination.
Patrick Affeldt, Felix Carlo Koehler, Karl August Brensing, Vivien Adam, Julia Burian, Linus Butt, Martin Gies, Franziska Grundmann, Steffen Hinrichs, Wibke Johannis, Nils Kalisch, Matthias Meyer-Delpho, Simon Oehm, Eva Platen, Claudia Schöler, Eva Heger, Gertrud Steger, Dirk Stippel, Aileen Ziegelhöfer, Thomas Benzing, Florian Klein, Christine Kurschat, Roman-Ulrich Müller, Veronica Di Cristanziano   +23 more
doaj   +1 more source

Effect of Newcastle disease virus level of infection on embryonic length, embryonic death, and protein profile changes [PDF]

Veterinary World, 2018
Background and Aim: Newcastle disease virus (NDV) is an obligate intracellular parasite. Virus can only live on living cells. The embryonated chicken eggs (ECEs) are one of the growth media of virus that is a cheap, easy to do, and accurate for showing ...
Dahliatul Qosimah, Sri Murwani, Edhy Sudjarwo, M. Arfan Lesmana   +3 more
doaj   +1 more source

Asbestos exposure and autoantibody titers

Annals of Occupational and Environmental Medicine, 2020
Asbestos is a well-known hazardous substance that causes occupational and environmental diseases including asbestosis (lung fibrosis). Silica exposure which causes silicosis (another type of lung fibrosis) has long been linked to the development of autoimmune diseases; however, there are few studies on the relationship between asbestos exposure and ...
Eunsoo Lee, Youngki Kim, Se Yeong Kim, Dongmug Kang   +3 more
openaire   +2 more sources

Improving the Yield and Quality of Daptomycin in Streptomyces roseosporus by Multilevel Metabolic Engineering

Frontiers in Microbiology, 2022
Daptomycin is a cyclic lipopeptide antibiotic with a significant antibacterial action against antibiotic-resistant Gram-positive bacteria. Despite numerous attempts to enhance daptomycin yield throughout the years, the production remains unsatisfactory ...
Zhong-Yuan Lyu, Zhong-Yuan Lyu, Qing-Ting Bu, Qing-Ting Bu, Jiao-Le Fang, Jiao-Le Fang, Chen-Yang Zhu, Chen-Yang Zhu, Wei-Feng Xu, Wei-Feng Xu, Lie Ma, Lie Ma, Wen-Li Gao, Wen-Li Gao, Xin-Ai Chen, Xin-Ai Chen, Yong-Quan Li, Yong-Quan Li   +17 more
doaj   +1 more source

Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS)

Biotechnology for Biofuels, 2020
BackgroundThe critical issue in the competitiveness between bioengineering and chemical engineering is the products titer and the volume productivity.
Xia Hua, Xin Zhou, Genlai Du, Yong Xu
semanticscholar   +1 more source

Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

mAbs, 2020
The success of monoclonal antibody (mAb) therapeutics have increased pharmaceutical investment in mAb production, which has led to a greater demand of technologies to efficiently characterize these biotherapeutics.
Zachary D. Dunn, Jayesh Desai, Gabriel M. Leme, Dwight R. Stoll, Douglas D. Richardson   +4 more
doaj   +1 more source

Immunogenicity evaluation of ChAdox1 nCov-19 (AZD1222) vaccine in solid cancer patients in Chulabhorn Hospital

Human Vaccines & Immunotherapeutics, 2022
Introduction Cancer patients are more vulnerable to coronavirus disease 2019 (COVID-19) owing to their compromised immune status. However, data regarding COVID-19 vaccine safety and immune response in cancer patients are scarce.
Piyarat Limpawittayakul, Prakongboon Sungkasubun, Worawit Chaiwiriyawong, Archara Supavavej, Bowon Weerasubpong, Jomtana Siripaibun, Chumut Phanthunane, Wisut Lamlertthon, Teerapat Ungtrakul, Kriangkrai Tawinprai, Walaipan Tantiyavarong, Chayanee Samdaengpan   +11 more
doaj   +1 more source

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning

Bioengineering, 2022
Improving productivity to reduce the cost of biologics manufacturing and ensure that therapeutics can reach more patients remains a major challenge faced by the biopharmaceutical industry.
Qin He, Matthew S. Rehmann, Jun Tian, Jianlin Xu, Luzmary Sabino, Erik Vandermark, Ziev Basson, Iris Po, Kathleen Bierilo, Gabi Tremml, Giovanni Rizzi, Erik F. Langsdorf, Nan-Xin Qian, Michael C. Borys, Anurag Khetan, Zheng-Jian Li   +15 more
doaj   +1 more source

Determination of 50% endpoint titer using a simple formula.

World Journal of Virology, 2016
Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary.
M. Ramakrishnan
semanticscholar   +1 more source