Results 61 to 70 of about 438,789 (339)

Changes in donor antibody titer levels over time in a military group O low‐titer whole blood program

Transfusion, 2019
The ability to rapidly administer whole blood (WB) at the point of injury is an important intervention to save lives. This can be accomplished using low titer group O WB donors. Titers of immunoglobulin M anti‐A and anti‐B might change over time.
Jonathan D. Bailey, Andrew D. Fisher, M. Yazer, Jeffrey T. Howard, Jason B. Corley, E. Miles, A. Cap   +6 more
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Anti-Phospholipase A2 Receptor Antibody Titer Predicts Post-Rituximab Outcome of Membranous Nephropathy.

Journal of the American Society of Nephrology, 2015
Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary membranous nephropathy (MN), even after other treatments have failed.
P. Ruggenenti, H. Dębiec, B. Ruggiero, Antonietta Chianca, Timotheé Pellé, F. Gaspari, Flavio Suardi, E. Gagliardini, S. Orisio, A. Benigni, P. Ronco, G. Remuzzi   +11 more
semanticscholar   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Counting rare Wolbachia endosymbionts using digital droplet PCR

Microbiology Spectrum
Wolbachia is the most widespread animal-associated intracellular microbe, living within the cells of over half of insect species. Since they can suppress pathogen replication and spread rapidly through insect populations, Wolbachia is at the vanguard of ...
Alphaxand K. Njogu, Francesca Logozzo, William R. Conner, J. Dylan Shropshire   +3 more
doaj   +1 more source

Simultaneous achievement of high ethanol yield and titer in Clostridium thermocellum

Biotechnology for Biofuels, 2016
BackgroundBiofuel production from plant cell walls offers the potential for sustainable and economically attractive alternatives to petroleum-based products.
Liang Tian, Beth Papanek, D. Olson, T. Rydzak, E. Holwerda, Tianyong Zheng, Jilai Zhou, Marybeth I. Maloney, Nannan Jiang, Richard J. Giannone, R. Hettich, A. Guss, L. Lynd   +12 more
semanticscholar   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals

Journal of Clinical Microbiology, 2018
Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
I. Mchardy, Bao-Tran Dinh, S. Waldman, Ethan R. Stewart, Derek J. Bays, D. Pappagianis, G. Thompson   +6 more
semanticscholar   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

Helicobacter pylori infection in subjects negative for high titer serum antibody

World Journal of Gastroenterology, 2018
AIM To investigate the clinicopathological features of the patients testing negative for high titer serum anti-Helicobacter pylori (H. pylori) antibody. METHODS The antibody titers were measured using antigens derived from Japanese individuals.
O. Toyoshima, T. Nishizawa, Masahide Arita, Yosuke Kataoka, Kosuke Sakitani, S. Yoshida, H. Yamashita, K. Hata, Hidenobu Watanabe, Hidekazu Suzuki   +9 more
semanticscholar   +1 more source