Results 71 to 80 of about 445,796 (343)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source

Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit

Journal of Nobel Medical College, 2020
Background: Health care workers are in high risk of getting infected with hepatitis B virus. A large proportion of them do not receive a 3-dose series of hepatitis B vaccination and have anti hepatitis B surface antibody titer  
Shailendra Shrestha, Pratap Roy
doaj   +1 more source

Metabolic engineering of Saccharomyces cerevisiae for efficient production of glucaric acid at high titer

Microbial Cell Factories, 2018
BackgroundGlucaric acid is a high-value-added chemical that can be used in various fields. Because chemical oxidation of glucose to produce glucaric acid is not environmentally friendly, microbial production has attracted increasing interest recently ...
Na Chen, Jingya Wang, Yunying Zhao, Yu Deng   +3 more
semanticscholar   +1 more source

Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi, Samantha N. Roman, Mohammad S. Sadaghiani, Lilja B. Solnes, Scott D. Newsome   +4 more
wiley   +1 more source

Antideoxyribonuclease B titers in psoriasis

Acta Dermato-Venereologica, 1980
Psoriatic patients were examined for serologic evidence of streptococcal infections by using antideoxyribonuclease B (ADB), which has been shown to be a more sensitive screening tool than antistreptolysin O (ASO) for detecting such evidence in other clinical circumstances.
S R, Quimby, H, Markowitz, R K, Winkelmann   +2 more
openaire   +2 more sources

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

The impact of host diet on Wolbachia titer in Drosophila. [PDF]

PLoS Pathogens, 2015
While a number of studies have identified host factors that influence endosymbiont titer, little is known concerning environmental influences on titer. Here we examined nutrient impact on maternally transmitted Wolbachia endosymbionts in Drosophila.
Laura R Serbus, Pamela M White, Jessica Pintado Silva, Amanda Rabe, Luis Teixeira, Roger Albertson, William Sullivan   +6 more
doaj   +1 more source

High titer heterologous rhamnolipid production

AMB Express, 2016
Heterologous mono-rhamnolipid production by Pseudomonas putida KT2440 pSynPro8oT_rhlAB using glucose as the single carbon source was characterized in fed-batch bioreactor cultivations. For the described experiments, a defined mineral salt medium was used, and a two phase glucose feeding profile was applied, which yielded a final rhamnolipid ...
Frank Rosenau, Theresa Barth, Andreas Wittgens, Janina Beuker, Janina Beuker, Anke Steier, Rudolf Hausmann, Marius Henkel   +7 more
openaire   +3 more sources

Evaluation of C1q Status and Titer of De Novo Donor‐Specific Antibodies as Predictors of Allograft Survival

American Journal of Transplantation, 2017
De novo donor‐specific antibodies (dnDSAs) that develop after renal transplantation are independent predictors of allograft loss. However, it is unknown if dnDSA C1q status or titer at the time of first detection can independently predict allograft loss.
Christopher R Wiebe, A. Gareau, D. Pochinco, I. Gibson, J. Ho, P. Birk, T. Blydt-Hansen, M. Karpinski, A. Goldberg, L. Storsley, D. Rush, P. Nickerson   +11 more
semanticscholar   +1 more source