Results 101 to 110 of about 656,654 (332)
MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY
Arthritis Care &Research, Accepted Article.Objective
Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of SPRING collaborators +77 morewiley +1 more sourceInfluence of Positive End-Expiratory Pressure Titration on the Effects of Pronation in Acute Respiratory Distress Syndrome: A Comprehensive Experimental Study
Frontiers in Physiology, 2020 Prone position can reduce mortality in acute respiratory distress syndrome (ARDS), but several studies found variable effects on oxygenation and lung mechanics.Gaetano Scaramuzzo, Gaetano Scaramuzzo, Lorenzo Ball, Lorenzo Ball, Fabio Pino, Fabio Pino, Lucia Ricci, Lucia Ricci, Anders Larsson, Claude Guérin, Claude Guérin, Claude Guérin, Paolo Pelosi, Paolo Pelosi, Gaetano Perchiazzi, Gaetano Perchiazzi +15 moredoaj +1 more sourceWater solubility in aluminosilicate melts of haplogranite composition at 2 kbar [PDF]
, 1992 The compositional dependence of H2O solubility was investigated at 2 kbar and 800°C in haplogranite melts (system SiO2---1bNaAlSi3O8---1bKAlSi3O8 or Qz---1bAb---1bOr).Blamart, Burnham, Burnham, Burnham, Day, Dingwell, Dingwell, Dingwell, Dingwell, Dingwell, Donald B. Dingwell, François Holtz, Friedman, Goranson, Hamilton, Harald Behrens, Holtz, Kennedy, Khitarov, Kohn, Lapham, Luth, Luth, McMillan, Mysen, Nabelek, Orlova, Oxtoby, Oxtoby, Pichavant, Pichavant, Pichavant, Richard P. Taylor, Silver, Silver, Stolper, Turek, Tuttle, Urbain, Voigt, Westrich, Zhang +41 morecore +1 more sourceTitration of mitochondrial fusion rescues Mff-deficient cardiomyopathy
Journal of Cell Biology, 2015 Mice deficient for mitochondrial fission factor (Mff) die from severe cardiomyopathy, but cardiac function, tissue integrity, and mitochondrial respiration are robustly rescued by rebalancing mitochondrial dynamics through deletion of Mitofusin 1 (Mfn1).Hsiuchen Chen, Shuxun Ren, Clary B. Clish, Mohit M. Jain, Vamsi K. Mootha, Vamsi K. Mootha, J. Mccaffery, D. C. Chan +7 moresemanticscholar +1 more sourceLipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue
Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas +12 morewiley +1 more sourceIdentification of a Histidine Metal Ligand in the \u3cem\u3eargE\u3c/em\u3e-Encoded \u3cem\u3eN\u3c/em\u3e-Acetyl-L-Ornithine Deacetylase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 2013 The H355A, H355K, H80A, and H80K mutant enzymes of the argE-encoded N-acetyl-L-ornithine deacetylase (ArgE) from Escherichia coli were prepared, however, only the H355A enzyme was found to be soluble. Kinetic analysis of the Co(II)-loaded H355A exhibited Gillner, Danuta, Holz, Richard C., Liu, Dali, McGregor, Wade C., Swierczek, Sabina I. +4 morecore +1 more sourceIndependent Ion Migration in Suspensions of Strongly Interacting Charged
Colloidal Spheres
, 2000 We report on sytematic measurements of the low frequency conductivity in
aequous supensions of highly charged colloidal spheres. System preparation in a
closed tubing system results in precisely controlled number densities between
1E16/m3 and 1E19/m^3 ...A. K. Sood, B. Jönsson, C. F. Zukoski, C. F. Zukoski, D. A. Saville, D. W. Schaefer, Dirk Hessinger, G. Nägele, H. Oshima, J. A. Davis, J. E. Seebergh, J. Lyklema, J. P. H. Zwetsloot, J. Stone-Masui, J. Yamanaka, J. Yamanaka, K. Ito, K. Sumaru, L. Belloni, L. P. Voegtli, M. A. Labib, M. Deggelmann, M. Evers, M. J. Stevens, M. O. Robbins, Martin Evers, R. A. Robinson, R. D. Groot, R. O. James, S. Alexander, S. Bucci, T. Bellini, T. Okubo, T. Palberg, T. Palberg, T. Palberg, T. Palberg, T. Palberg, T. Palberg, T. Palberg, Thomas Palberg, U. Apfel, V. Degiorgio +42 morecore +1 more sourceBiomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions
Advanced Functional Materials, EarlyView.This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron Wenjie Tian, Jingkai Lin, Zhihao Tian, Selusiwe Ncube, Huayang Zhang, Emiliano Cortés, Hongqi Sun, Shaobin Wang +7 morewiley +1 more sourceDevelopment of a fast screening method for the direct determination of chlorinated persistent organic pollutants in fish oil by high-resolution continuum source graphite furnace molecular absorption spectrometry [PDF]
, 2017 The authors are grateful to the Conselho Nacional de Desenvolvimento Científico and Tecnológico (CNPq); the present research was mostly financed through Project no. CNPq 406877/2013-0.Cadorim, Heloisa R., Campo Menoyo, Javier Del, Carvalho, Gabriel S., Duarte, Fabio A., Feldmann, Jorg, Merib, Josias, Pereira, Éderson R, Schneider, Mauana, Welz, Bernhard +8 morecore +1 more source