Results 121 to 130 of about 5,311 (156)

Reproductive toxic effects of Tityus serrulatus scorpion venom in rats

Reproductive Toxicology, 2008
Tityus serrulatus is the most venomous scorpion in Brazil. Little is known about the effect of maternal exposure to the venom on fetal development. We investigated the effect of low to moderate doses of the venom (0.3 or 1.0 mg/kg s.c. on either day 5 or day 10 of gestation) on pregnant rats and on their offspring.
Karen, Cruttenden, Ana Leonor A, Nencioni, Maria Martha, Bernardi, Valquiria A C, Dorce   +3 more
openaire   +2 more sources

Lung oedema induced by Tityus serrulatus scorpion venom in the rat

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1997
The effects of drugs were investigated on the induction of acute lung oedema by scorpion Tityus serrulatus venom in male Wistar rats (200-230 g) anaesthetized with sodium pentobarbital (40 mg/kg, i.p.). Intravenous (i.v.) injection of scorpion venom (0.5 mg/kg) into 12 rats induced arterial hypertension and severe lung oedema, whereas i.v. injection of
I M, De Matos, O A, Rocha, R, Leite, L, Freire-Maia   +3 more
openaire   +2 more sources

Immune cells recruitment and activation by Tityus serrulatus scorpion venom

Toxicon, 2011
Despite several studies showed that the Tityus serrulatus scorpion venom (Tsv) induces an inflammatory response, just a few have investigated the effect of the venom on the immune response. Therefore, the aim of this study was to evaluate alterations of venom application on lymphoid organs and on the recruitment and activation of cells and also on the ...
Eder M S, Fialho, Márcia C G, Maciel, Arlley C B, Silva, Aramys S, Reis, Anne Karine M, Assunção, Thiare S, Fortes, Lucilene A, Silva, Rosane N M, Guerra, Fabio H, Kwasniewski, Flávia R F, Nascimento   +9 more
openaire   +2 more sources

Clinical consequences of Tityus bahiensis and Tityus serrulatus scorpion stings in the region of Campinas, southeastern Brazil

Toxicon, 2014
Scorpion stings account for most envenomations by venomous animals in Brazil. A retrospective study (1994-2011) of the clinical consequences of Tityus scorpion stings in 1327 patients treated at a university hospital in Campinas, southeastern Brazil, is reported.
Fábio, Bucaretchi, Luciane C R, Fernandes, Carla B, Fernandes, Maíra M, Branco, Camila C, Prado, Ronan J, Vieira, Eduardo M, De Capitani, Stephen, Hyslop   +7 more
openaire   +2 more sources

Effect of the venom of the scorpion Tityus serrulatus on adrenal gland catecholamines

Toxicon, 1968
Abstract A sublethal dose of the venom of the scorpion Tityus serrulatus produced a depletion of adrenal gland catecholamines. This effect was blocked on denervation of the adrenals. The action of the venom on the chromaffin granules in vitro was not observed. Certain fractions of the venom elicited the same effects as the whole venom.
M C, Henriques, G, Gazzinelli, C R, Diniz, M V, Gomez   +3 more
openaire   +2 more sources

Renal effects and vascular reactivity induced by Tityus serrulatus venom

Toxicon, 2005
Tityus serrulatus, popularly known as yellow scorpion, is one of the most studied scorpion species in South America and its venom has supplied some highly active molecules. The effects of T. serrulatus venom upon the renal physiology in human showed increased renal parameters, urea and creatinine.
Alves, R. D., do Nascimento, NRF, Barbosa, PSF, Kerntopf, M. R., Lessa, LMA, de Sousa, C. M., Martins, R. D., Sousa, D. F., de Queiroz, MGR, Toyama, M. H., Fonteles, M. C., Martins, AMC, Monteiro, HSA   +12 more
openaire   +3 more sources

The effect of dithiothreitol on the activity of tityustoxin from the scorpion Tityus serrulatus venom

Toxicology Letters, 1994
The acetylcholine (ACh) liberating effect on rat brain slices of tityustoxin, an alpha toxin from the scorpion Tityus serrulatus venom, was measured in the absence and presence of dithiothreitol (DTT). The rate of net ACh liberation by toxin concentrations of 2 nmol in 5 ml of organ bath, was 7.5 +/- 0.09 nmol g-1 min-1. If DTT at a final concentration
A M, Silva, G, Novaes, I F, Heneine
openaire   +2 more sources

Activation of the complement system and leukocyte recruitment by Tityus serrulatus scorpion venom

International Immunopharmacology, 2005
The scorpion Tityus serrulatus is considered one of the most dangerous species in Brazil. Its venom evokes an inflammatory response, although the exact mechanism of this effect is still unknown. The aim of the present study was to investigate the effect of Tityus serrulatus venom (TsV) on the complement system (CS) and on leukocyte recruitment ...
Daniela Trinca, Bertazzi, Ana Isabel, de Assis-Pandochi, Vinicius Luis, Talhaferro, Ana Elisa, Caleiro Seixas Azzolini, Luciana Simon, Pereira Crott, Eliane Candiani, Arantes   +5 more
openaire   +2 more sources

Acute pulmonary edema after Tityus serrulatus scorpion sting in children

The American Journal of Cardiology, 1993
Acute pulmonary edema due to scorpion toxins has been attributed to acute left ventricular failure resulting from massive catecholamine release or myocardial damage induced by the venom.1–3 It has been proposed that pulmonary edema could also result from increased pulmonary vascular permeability produced by vasoactive substances that may be released by
C F, Amaral, N A, de Rezende, L, Freire-Maia   +2 more
openaire   +2 more sources

Ipomoea asarifolia neutralizes inflammation induced by Tityus serrulatus scorpion venom

Journal of Ethnopharmacology, 2014
Envenoming caused by scorpion sting is a serious public health problem. In Brazil, 13,038 accidents caused by venomous animals have been reported. Of this total, 53% of the cases and 14 deaths were caused by scorpions. Furthermore, Tityus serrulatus (Buthidae) is the most dangerous scorpion due to the high toxicity of its venom.
Maira Conceição Jerônimo de Souza, Lima, Mariana Angélica Oliveira, Bitencourt, Allanny Alves, Furtado, Hugo Alexandre, Oliveira Rocha, Ruth Medeiros, Oliveira, Arnóbio Antônio, da Silva-Júnior, Eryvaldo Sócrates, Tabosa do Egito, Denise Vilarinho, Tambourgi, Silvana Maria, Zucolotto, Matheus de Freitas, Fernandes-Pedrosa   +9 more
openaire   +2 more sources