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Technetium-99m labeling of tityustoxin and venom from the scorpion Tityus serrulatus
Applied Radiation and Isotopes, 2002The tityustoxin, the most toxic fraction from scorpion Tityus serrulatus venom, has been used as a tool in several neurochemical and neuropharmacological studies. Biological activities of labeled and unlabeled tityustoxin and venom were compared. The samples were labeled in the presence of stannous chloride and sodium borohydride with a yield of 60-70%
Valbert Nascimento Cardoso +2 more
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Peripheral Effects ofTityus serrulatusScorpion Venom
Journal of Toxicology: Toxin Reviews, 1995AbstractIn this review we describe the peripheral effects induced by Tityus serrulatus scorpion venom and two of the most important toxins-tityustoxin and toxin Ts-γ purified from the crude venom. The complex cardiac arrhythmias elicited by the venom or the toxins were explained by the release of catecholamines and acetylcholine. In isolated rat atria,
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Toxicology Letters, 1994
The acetylcholine (ACh) liberating effect on rat brain slices of tityustoxin, an alpha toxin from the scorpion Tityus serrulatus venom, was measured in the absence and presence of dithiothreitol (DTT). The rate of net ACh liberation by toxin concentrations of 2 nmol in 5 ml of organ bath, was 7.5 +/- 0.09 nmol g-1 min-1. If DTT at a final concentration
Geovanna Novaes +2 more
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The acetylcholine (ACh) liberating effect on rat brain slices of tityustoxin, an alpha toxin from the scorpion Tityus serrulatus venom, was measured in the absence and presence of dithiothreitol (DTT). The rate of net ACh liberation by toxin concentrations of 2 nmol in 5 ml of organ bath, was 7.5 +/- 0.09 nmol g-1 min-1. If DTT at a final concentration
Geovanna Novaes +2 more
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Activation of the complement system and leukocyte recruitment by Tityus serrulatus scorpion venom
International Immunopharmacology, 2005The scorpion Tityus serrulatus is considered one of the most dangerous species in Brazil. Its venom evokes an inflammatory response, although the exact mechanism of this effect is still unknown. The aim of the present study was to investigate the effect of Tityus serrulatus venom (TsV) on the complement system (CS) and on leukocyte recruitment ...
A.I. Assis-Pandochi +5 more
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Severe scorpion envenomalion in children caused by Tityus bahiensis and Tityus serrulatus
Toxicon, 1995Márcia R. C. C. Fonseca +4 more
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Isolation of a Bradykinin-Potentiating Factor from Scorpion Tityus Serrulatus Venom
1992A bradykinin-potentiating factor was isolated and characterized from the scorpion Tityus serrulatus venom by chromatographic techniques and reverse phase followed by biological assays. This factor showed to be able to potentiate the contractile activity of the isolated guinea-pig ileum, inhibited the angiotensin-converting enzyme and potentiated the ...
Henriques Ob, Ferreira La
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Scorpion Venom Research Around the World: Tityus serrulatus [PDF]
, 2014 Eliane Candiani Arantes +3 more
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