Results 31 to 40 of about 119,061 (97)

Actinium-225 targeted alpha particle therapy for prostate cancer

Theranostics
Targeted alpha particle therapy (TAT) has emerged as a promising strategy for the treatment of prostate cancer (PCa). Actinium-225 (225Ac), a potent alpha-emitting radionuclide, may be incorporated into targeting vectors, causing robust and in some cases
A. Bidkar, Luann Zerefa, Surekha Yadav, H. VanBrocklin, R. Flavell   +4 more
semanticscholar   +1 more source

Supply and Clinical Application of Actinium-225 and Bismuth-213

Seminars in nuclear medicine, 2020
The recent development of 225Ac-PSMA617 for therapy of prostate cancer has strikingly demonstrated the clinical potential of targeted alpha therapy. Further promising applications of the alpha emitters 225Actinium and its daughter nuclide 213Bismuth ...
A. Morgenstern, C. Apostolidis, F. Bruchertseifer   +2 more
semanticscholar   +1 more source

Real-time trajectory imaging of alpha particles emitted from actinium-225 and its daughter radionuclides

Scientific Reports
In targeted alpha-particle therapy, actinium-225 (Ac-225) has emerged as a radionuclide of potential, driving extensive efforts to develop innovative radiopharmaceuticals.
S. Yamamoto, Masao Yoshino, K. Shirasaki, K. Nakanishi, Kei Kamada, Akira Yoshikawa, J. Kataoka   +6 more
semanticscholar   +1 more source

Control robusto H-infinito para la velocidad de desplazamiento de un UAV en base a estimación de flujo óptico

Revista Iberoamericana de Automática e Informática Industrial RIAI, 2021
Se presenta el diseño del control para la velocidad de desplazamiento de un vehículo aéreo de seis rotores. La técnica de diseño utilizada es el control óptimo en H–infinito con el objetivo de conseguir rendimiento robusto ante la incertidumbre en el ...
A.S. Ghersin, J.I. Giribet, J. Luiso, A. Tournour   +3 more
doaj   +1 more source

Tumor targeted alpha particle therapy with an actinium-225 labelled antibody for carbonic anhydrase IX

Chemical Science
Selective antibody targeted delivery of α particle emitting actinium-225 to tumors has significant therapeutic potential. This work highlights the design and synthesis of a new bifunctional macrocyclic diazacrown ether chelator, H2MacropaSqOEt, that can ...
Katherine A Morgan, C. Wichmann, Laura D Osellame, Zhipeng Cao, N. Guo, Andrew M Scott, Paul S Donnelly   +6 more
semanticscholar   +1 more source

In-House Preparation and Quality Control of Ac-225 Prostate-Specific Membrane Antigen-617 for the Targeted Alpha Therapy of Castration-Resistant Prostate Carcinoma

Indian Journal of Nuclear Medicine, 2021
Purpose: Ac-225 labeled with prostate-specific membrane antigen (PSMA-617), a transmembrane glycoprotein which is highly expressed in prostate carcinoma cells, is presently being considered a promising agent of targeted alpha therapy for the treatment of
Parul Thakral, J. Šimeček, Sebastian Marx, Jyotsna Kumari, Vineet Pant, I. Sen   +5 more
semanticscholar   +1 more source

Actinium-225 in Targeted Alpha Therapy

Journal of Medical Physics
The utilization of actinium-225 (225Ac) radionuclides in targeted alpha therapy for cancer was initially outlined in 1993. Over the past two decades, substantial research has been conducted, encompassing the establishment of 225Ac production methods ...
A. K. M. R. Rahman, Mahathe Hasan Babu, Mustofa Khalid Ovi, Md. Mahiuddin Zilani, Israt Sultana Eithu, Amit Chakraborty   +5 more
semanticscholar   +1 more source

Improved multiverse optimizer‐based anti‐saturation model free adaptive control and its application to manipulator grasping systems

IET Control Theory & Applications
To address the stable grasping control issue in manipulator grasping systems, this manuscript proposes an improved multiverse optimizer‐based anti‐saturation model‐free adaptive control (IMVO‐AS‐MFAC) algorithm.
Shida Liu, Zhen Li, Jiancheng Li, Honghai Ji, Jingquan He   +4 more
doaj   +1 more source

Modeling the effect of daughter migration on dosimetry estimates for unlabeled actinium-225.

Medical Physics (Lancaster)
BACKGROUND Actinium-225 (225 Ac) is an alpha emitting radionuclide which has demonstrated promising results in Targeted Alpha Therapy (TAT). A concern with 225 Ac is that the decay energy can break the bond to the targeting vehicle, resulting in the ...
Stephen Tronchin, J. Forster, Kevin Hickson, Eva Bezak   +3 more
semanticscholar   +1 more source

Data‐driven Buck converter model identification method with missing outputs

IET Control Theory & Applications
A data‐driven Buck converter model identification method is proposed to deal with missing (incomplete) outputs, which is robust to the data length and percentage of missing data.
Jie Hou, Xinhua Zhang, Huiming Wang, Shiwei Wang   +3 more
doaj   +1 more source