Results 141 to 150 of about 719 (168)

Applications and limitations of AI tools in enzyme design

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Enzymes catalyze various different chemical reactions often with high efficiency and selectivity compared to synthetic catalysts. Advances in protein engineering over the past decades have allowed researchers to design enzymes, improving their catalytic performance and adapting them for specific or entirely novel chemical reactions.
Rosa Teijeiro‐Juiz, Nina Egeler, Grzegorz Jamróg, Marion Ringel, Thomas Brück, Bruno Di Geronimo, Bernhard Loll   +6 more
wiley   +1 more source

Knowledge-Graph-Driven Fault Diagnosis Methods for Intelligent Production Lines. [PDF]

Sensors (Basel)
Chen Y, Zhou M, Zhang M, Zha M.
europepmc   +1 more source

A Tale of Two Cell Lines: Characterization of Differential Efficacy of Small Molecule Drugs Cediranib and NU‐7441 on Primary Versus Metastatic Colorectal Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Colorectal cancer is recognized as one of the leading causes of cancer death amongst both sexes in the U.S. Despite rigorous screening, those diagnosed with colon cancer often face poor prognosis, and approximately 70% of affected patients will develop metastatic relapse. The investigation of colon carcinoma cell lines' genetic variability and
Josephine D. Tsang, Cai M. Roberts
wiley   +1 more source

Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies. [PDF]

J Nanobiotechnology
Mehdizadeh S, Mamaghani M, Hassanikia S, Pilehvar Y, Ertas YN.   +4 more
europepmc   +1 more source

Biophysical perspectives to understanding cancer-associated fibroblasts. [PDF]

APL Bioeng
Devarasou S, Kang M, Shin JH.
europepmc   +1 more source

Neuroinflammatory stress preferentially impacts synaptic MAPK signaling and mitochondria in excitatory neurons. [PDF]

Mol Neurodegener Adv
Espinosa-Garcia C, Srivastava U, Kumar P, Kour D, Malepati S, Tobin BR, Xiao H, Sunna S, Bowen CA, Cheng L, Bagchi P, Duong DM, Whitworth TJ, Liu X, Seyfried NT, Wood LB, Faundez V, Rangaraju S.   +17 more
europepmc   +1 more source

Fusing multiple source data for foundation excavation risk assessment based on cloud model and Dempster Shafer evidence theory. [PDF]

Sci Rep
An Y, Li L, Gao H, Luo Z, He Y.
europepmc   +1 more source

ZO-2 is a scaffold at the centriole and mitotic spindle poles that enhances microtubule stability and supports the proper development of mitotic spindles and cilia. [PDF]

Cell Tissue Res
Vega-Torreblanca S, Pinto-Dueñas DC, Hernández-Guzmán C, Martín-Tapia D, Alarcón L, Chávez-Munguía B, Salazar-Villatoro L, González-Pozos S, Hernández-Varela JD, Ramírez-Martínez L, López-Bayghen E, Chanona-Pérez JJ, González-Mariscal L.   +12 more
europepmc   +1 more source

Direct cell-to-cell transmission of retrotransposons

Voichek M, Bernhard A, Novatchkova M, Handler D, Möseneder P, Rafanel B, Duchek P, Senti K, Brennecke J.   +8 more
europepmc   +1 more source