Results 161 to 170 of about 30,377 (206)

An Anoikis Resistance Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Blockades in Gastric Cancer

Cancer Innovation, Volume 5, Issue 1, February 2026.
Gastric cancer (GC) has high global incidence and mortality, with most cases diagnosed at advanced stages. Immunotherapy, particularly immune checkpoint blockers (ICBs), has shown promise, but not all patients benefit. This study applied consensus clustering based on anoikis‐related genes (ANRGs) to classify GC into two subclusters.
Xing Cai, Jinru Yang, Fangyuan Zhang, Fuwang Xu, Yuan Fang, Zongbi Yi   +5 more
wiley   +1 more source

Integrin force loading rate in mechanobiology: From model to molecular measurement. [PDF]

QRB Discov
Zhang H, Yang M, Kim SH, Li ITS.
europepmc   +1 more source

European Economy Supplement B No. 2-February 1986. Economic prospects-business and consumer survey results [PDF]

, 1986

core  

CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
CEACAM6 has the potential to become a novel and independent prognostic biomarker in cholangiocarcinoma (CCA). Silencing CEACAM6 can inhibit CCA tumour growth and significantly enhance the chemosensitivity to cisplatin. This chemo‐sensitising effect is mediated through the disruption of ribosome biogenesis and impairment of DNA damage repair.
Shi‐Jia Dai, Jiang‐Qi Tan, Jia‐Qi Guo, Ya‐Nan Zhou, Teng Huang, Hao‐Lin Jiang, Yang Liu, Li‐Wei Dong, Zhen‐Gang Yuan   +8 more
wiley   +1 more source

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, Volume 11, Issue 1, Page 347-362, February 2026.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Crystallizing the Uncrystallizable: Insights from Extensive Screening of PROTACs. [PDF]

J Am Chem Soc
Screen MA, McCabe JF, Askin S, Guest JL, Hodgkinson P, Cruz-Cabeza AJ, Blundell TJ, Rainer DN, Coles SJ, Longcake A, Probert MR, Mahon CS, Wilson MR, Steed JW.   +13 more
europepmc   +1 more source

iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT There are a number of guidelines on how to manage obesity, but inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices restrict their global applicability. This underscores the need for universal recommendations that address the unique challenges faced by patients and healthcare providers ...
Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J. S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuan‐Lin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed, Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano, Nandini Chatterjee, Marc‐André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M. C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Martha Gulati, Naveed Sattar, Jose Luis Zamorano   +60 more
wiley   +1 more source

Pathogenesis, Diagnosis, and Treatment of Infectious Rhinosinusitis. [PDF]

Microorganisms
Huang F, Liu F, Zhen X, Gong S, Chen W, Song Z.   +5 more
europepmc   +1 more source

Machine learning model for fast prediction and uncertainty quantification of needle deflection during prostate biopsy

Medical Physics, Volume 53, Issue 2, February 2026.
Abstract Background Accurate needle placement is essential for prostate biopsy. Recently, transperineal prostate biopsies are receiving renewed interest due to concern over infection from conventional transrectal biopsies. However, accurate needle placement is more challenging in the transperineal approach than in the transrectal approach due to the ...
Nathan Hoffman, Lidia Al‐Zogbi, Axel Krieger, Junichi Tokuda, Pedro Moreira, Mark Fuge   +5 more
wiley   +1 more source

Technology Roadmap of Micro/Nanorobots. [PDF]

ACS Nano
Ju X, Chen C, Oral CM, Sevim S, Golestanian R, Sun M, Bouzari N, Lin X, Urso M, Nam JS, Cho Y, Peng X, Landers FC, Yang S, Adibi A, Taz N, Wittkowski R, Ahmed D, Wang W, Magdanz V, Medina-Sánchez M, Guix M, Bari N, Behkam B, Kapral R, Huang Y, Tang J, Wang B, Morozov K, Leshansky A, Abbasi SA, Choi H, Ghosh S, Borges Fernandes B, Battaglia G, Fischer P, Ghosh A, Jurado Sánchez B, Escarpa A, Martinet Q, Palacci J, Lauga E, Moran J, Ramos-Docampo MA, Städler B, Herrera Restrepo RS, Yossifon G, Nicholas JD, Ignés-Mullol J, Puigmartí-Luis J, Liu Y, Zarzar LD, Shields CW, Li L, Li S, Ma X, Gracias DH, Velev O, Sánchez S, Esplandiu MJ, Simmchen J, Lobosco A, Misra S, Wu Z, Li J, Kuhn A, Nourhani A, Maric T, Xiong Z, Aghakhani A, Mei Y, Tu Y, Peng F, Diller E, Sakar MS, Sen A, Law J, Sun Y, Pena-Francesch A, Villa K, Li H, Fan DE, Liang K, Huang TJ, Chen XZ, Tang S, Zhang X, Cui J, Wang H, Gao W, Kumar Bandari V, Schmidt OG, Wu X, Guan J, Sitti M, Nelson BJ, Pané S, Zhang L, Shahsavan H, He Q, Kim ID, Wang J, Pumera M.   +102 more
europepmc   +1 more source