Results 31 to 40 of about 163,856 (247)

Der verpflichtete Patient

open access: yesMonitor Versorgungsforschung
Im Spätsommer soll ein Referentenentwurf für ein verbindliches Primärversorgungssystem vorliegen. Im Ziel sind sich Koalition, Krankenkassen und Ärzteschaft einig, doch wer steuern soll und wie verbindlich das geschieht, ist heftig umstritten.
Peter Stegmaier   +1 more
doaj   +1 more source

PENERAPAN METODE BERMAIN PERANDALAM MENINGKATKAN KEMAMPUAN BERBAHASAANAK USIA 5-6 TAHUN DI TK KARTIKA 1-4 PEKANBARU

open access: yesPrimary: Jurnal Pendidikan Guru Sekolah Dasar, 2016
Background this study is the most difficult children tell in their own words about the practice or an event that happened, for example when they told me about their experiences. Their most difficult child listening to the teacher.
Henik Srihayati
doaj   +1 more source

Simulasi Rasa Percaya Diri Dengan Kegiatan Tarian Saronde Pada Anak Taman Kanak-Kanak

open access: yesJurnal Educatio FKIP UNMA, 2021
Rasa percaya diri adalah modal dasar seorang anak manusia dalam memenuhi berbagai kebutuhannya. Tari Saronde merupakan tarian yang diangkat dari tradisi pernikahan adat masyarakat Gorontalo.
Yolan Marjuk   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Solar-TK [PDF]

open access: yesProceedings of the 6th ACM International Conference on Systems for Energy-Efficient Buildings, Cities, and Transportation, 2019
There has been significant prior work on solar performance modeling and forecasting that infers a site's current and future solar generation based on different factors including a site's location, time, weather, and physical attributes. Unfortunately, much of the prior work is not accessible to researchers, either because it has not been implemented ...
Noman Bashir   +3 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Pemanfaatan Barang Bekas dalam Meningkatkan Kemampuan Motorik Halus Anak

open access: yesAṭfālunā, 2019
This research aims to improve the children’s fine motor skills by using used goods. The medium was the bottle caps of mineral water that were arranged into various goods of art.
Siti Maghfirah
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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