Results 1 to 10 of about 576,830 (232)
Journal of Experimental Life Science, 2018 Koi herpesvirus (KHV) is a virus that usually infects carp and koi causing mass mortality, as well as economic and social loss. The results of varied test are often found in its development.
Amira Baihani +2 more
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Intestinal epithelial stem/progenitor cells are controlled by mucosal afferent nerves. [PDF]
PLoS ONE, 2011 BACKGROUND: The maintenance of the intestinal epithelium is of great importance for the survival of the organism. A possible nervous control of epithelial cell renewal was studied in rats and mice.
Ove Lundgren +4 more
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Thymidine Kinase in IDU Resistance.
Experimental Biology and Medicine, 1965 SummaryStudies were done to determine whether 5-iodo-2′-deoxyuridine resistance of herpes simplex in rabbit corneal infection was a function of thymidine kinase deficiency in the viral genome. Herpes simplex virus passed in rabbit kidney cells in the presence of 5-iodo-2′-deoxyuridine was resistant to it in vivo although this resistant virus induced ...
Y, Centifanto, H E, Kaufman
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Thymidine uptake, thymidine incorporation, and thymidine kinase activity in marine bacterium isolates [PDF]
Applied and Environmental Microbiology, 1990 One assumption made in bacterial production estimates from [3H]thymidine incorporation is that all heterotrophic bacteria can incorporate exogenous thymidine into DNA. Heterotrophic marine bacterium isolates from Tampa Bay, Fla., Chesapeake Bay, Md., and a coral surface microlayer were examined for thymidine uptake (transport), thymidine incorporation,
W H, Jeffrey, J H, Paul
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Limits of [18F]-FLT PET as a biomarker of proliferation in oncology. [PDF]
PLoS ONE, 2013 Non-invasive imaging biomarkers of cellular proliferation hold great promise for quantifying response to personalized medicine in oncology. An emerging approach to assess tumor proliferation utilizes the positron emission tomography (PET) tracer 3'-deoxy-
Eliot T McKinley +7 more
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In silico investigation of acyclovir derivatives potency against herpes simplex virus
Scientific African, 2023 Herpes simplex virus (HSV) is a major human pathogen, sub-divided into two types: HSV-1 which causes oral and perioral infections and HSV-2 which causes genital herpes.
Clive M. Nyaribo +2 more
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PLoS ONE, 2019 Plasmodium falciparum thymidylate kinase (PfTMK) showed structural and catalytic distinctions from the host enzyme rendering it a hopeful antiprotozoal drug target.
Mahmoud Kandeel +3 more
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Molecular Therapy: Oncolytics, 2022 Glioblastoma multiforme (GBM) is the most invasive form of primary brain astrocytoma. Gene therapy using the herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) is a new strategy for GBM treatment.
Saereh Hosseindoost +6 more
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Inhibition of Thymidine Kinase by Cortisone
Experimental Biology and Medicine, 1970 SummaryIn vivo and in vitro studies revealed that incorporation of thymidine-3H into DNA was inhibited in Ehrlich ascites cells treated with cortisone 24 hr before. Incorporations of other DNA precursors were not inhibited. Thymidine kinase was markedly inhibited by pretreatment with cortisone.
T, Kaneko, G A, LePage
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Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency
EMBO Molecular Medicine, 2014 Autosomal recessive mutations in the thymidine kinase 2 gene (TK2) cause mitochondrial DNA depletion, multiple deletions, or both due to loss of TK2 enzyme activity and ensuing unbalanced deoxynucleotide triphosphate (dNTP) pools.
Caterina Garone +8 more
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