Results 21 to 30 of about 107,915 (237)

Evidence that host size determines liver size: Studies in dogs receiving orthotopic liver transplants [PDF]

, 1987
Orthotopic liver transplantation was performed in two groups of dogs; Group I animals consisted of large dogs that served as recipients of livers obtained from smaller dogs while Group II animals consisted of dogs that received liver from donor dogs of ...
Bucher, Bucher, Kahn, Koch, Leffert, Leffert, Leffert, McGowan, Morley, Putman, Richman, Rubin, Russell, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Strecker, Van Thiel, Van Thiel, Wagle   +28 more
core   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Akada, Allison, Almoguera, Andreetta, Arai, Arlt, Arteaga, Arumugam, Asano, Bachem, Baldwin, Banerjee, Bartsch, Bergers, Best, Bold, Bondar, Buck, Burris, Chakravarti, Chakravarti, Choi, Cunningham, Cunningham, Dancer, Dong, Duxbury, Duxbury, Duxbury, Duxbury, Engelman, Feldmann, Ferrero, Galmarini, Geyer, Giovannetti, Goan, Greer, Hagmann, Hahn, Henke, Hruban, Humeniuk, Ischenko, Ishikawa, Itoi, Jansen, Karapetis, Kindler, Kong, Koopman, Kulik, Lei, Lemoine, Liau, Liau, Longley, Mackey, Mackey, Mackey, Mahon, Mamaghani, Marechal, Marmor, Martin Clynes, Mata, Maxwell, Mendelsohn, Meropol, Miwa, Moertel, Molina-Arcas, Moore, Morgillo, Moriyama, Muerkoster, Muerkoster, Nakahira, Nakajima, Nakano, Naomi Walsh, Nishimura, Oguri, Okamoto, Okumura, Olive, O’Driscoll, Pao, Park, Park, Peters, Plunkett, Ray McDermott, Ritzel, Rizwan Sheikh, Robert O’Connor, Ruggeri, Safran, Saito, Sakamoto, Schuller, Sebastiani, Shah, Shi, Simon, Spratlin, Takao, Takebayashi, Treat, Tsukamoto, Tzeng, Vaishampayan, Van Cutsem, van der Wilt, Wang, Wang, Wang, Xiong, Yamasaki, Yokoi   +119 more
core   +1 more source

Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders

BMC Neuroscience, 2022
Background Deoxythymidine triphosphate (dTTP) is an essential building block of DNA, and defects in enzymes involved in dTTP synthesis cause neurodegenerative disorders.
Junmei Hu Frisk, Stefan Örn, Gunnar Pejler, Staffan Eriksson, Liya Wang   +4 more
doaj   +1 more source

Tunneling nanotubes: an alternate route for propagation of the bystander effect following oncolytic viral infection

Molecular Therapy: Oncolytics, 2016
Tunneling nanotubes (TNTs) are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances.
Justin Ady, Venugopal Thayanithy, Kelly Mojica, Phillip Wong, Joshua Carson, Prassanna Rao, Yuman Fong, Emil Lou   +7 more
doaj   +1 more source

Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields [PDF]

, 2002
BACKGROUND: The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased incidence of leukaemia in parts of the population exposed to ...
Harris, Paul A., Heaton, Brian, Lamb, Justin, Wheatley, Denys N.   +3 more
core   +3 more sources

The diagnostic value of serum microRNA-183 and TK1 as biomarkers for colorectal cancer diagnosis

Open Life Sciences, 2017
To evaluate the serum levels of microRNA-183 (miR-183) and thymidine kinase 1 (TK1) in colorectal cancer patients and their clinical value as biomarkers for colorectal cancer auxiliary diagnosis.
Zhu Xiangrong, Wang Xiongtie, Chen Xihua
doaj   +1 more source

Thymidine kinase 1 through the ages: a comprehensive review

Cell & Bioscience, 2020
Proliferation markers, such as proliferating cell nuclear antigen (PCNA), Ki-67, and thymidine kinase 1 (TK1), have potential as diagnostic tools and as prognostic factors in assessing cancer treatment and disease progression. TK1 is involved in cellular
Eliza E. Bitter, Michelle H. Townsend, Rachel Erickson, Carolyn Allen, Kim L. O’Neill   +4 more
doaj   +1 more source

Thymidine kinase in breast cancer [PDF]

British Journal of Cancer, 1990
The enzyme thymidine kinase is associated with DNA synthesis. Thymidine kinase serum levels were studied in normal controls (n = 20), patients with primary breast cancer (n = 60), patients with systemic breast cancer (n = 20) and as a non-cancer disease control group in patients with inflammatory gastrointestinal disorders (n = 20).
J F, Robertson, K L, O'Neill, M W, Thomas, P G, McKenna, R W, Blamey   +4 more
openaire   +2 more sources

Serum Thymidine Kinase (TK) Evaluation in HIV Infection

The International Journal of Biological Markers, 1989
Serum thymidine kinase (TK), measured using Prolifigen TK-REA, from AB Sangtec Medical, was investigated in 24 HIV seropositive patients without immunological alterations, 26 seropositives with immunological alterations, 125 LAS, 25 ARC, and 20 AIDS ...
S. Sabbatani, A. Fini, E. Raise, F.M. Gritti   +3 more
doaj   +1 more source

Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions

Cardiovascular Diabetology, 2007
Background Inhibition of vascular smooth muscle cell (vSMC) proliferation by oral anti-hyperglycemic agents may have a role to play in the amelioration of vascular disease in diabetes.
de Dios Stephanie T, Osman Narin, Little Peter J, Cemerlang Nelly, Ballinger Mandy, Nigro Julie   +5 more
doaj   +1 more source