Results 31 to 40 of about 67,342 (249)
BMC Neuroscience, 2022 Background Deoxythymidine triphosphate (dTTP) is an essential building block of DNA, and defects in enzymes involved in dTTP synthesis cause neurodegenerative disorders.
Junmei Hu Frisk +4 more
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Molecular Therapy: Oncolytics, 2016 Tunneling nanotubes (TNTs) are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances.
Justin Ady +7 more
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The diagnostic value of serum microRNA-183 and TK1 as biomarkers for colorectal cancer diagnosis
Open Life Sciences, 2017 To evaluate the serum levels of microRNA-183 (miR-183) and thymidine kinase 1 (TK1) in colorectal cancer patients and their clinical value as biomarkers for colorectal cancer auxiliary diagnosis.
Zhu Xiangrong, Wang Xiongtie, Chen Xihua
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Thymidine kinase 1 through the ages: a comprehensive review
Cell & Bioscience, 2020 Proliferation markers, such as proliferating cell nuclear antigen (PCNA), Ki-67, and thymidine kinase 1 (TK1), have potential as diagnostic tools and as prognostic factors in assessing cancer treatment and disease progression. TK1 is involved in cellular
Eliza E. Bitter +4 more
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Serum Thymidine Kinase (TK) Evaluation in HIV Infection
The International Journal of Biological Markers, 1989 Serum thymidine kinase (TK), measured using Prolifigen TK-REA, from AB Sangtec Medical, was investigated in 24 HIV seropositive patients without immunological alterations, 26 seropositives with immunological alterations, 125 LAS, 25 ARC, and 20 AIDS ...
S. Sabbatani +3 more
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Cardiovascular Diabetology, 2007 Background Inhibition of vascular smooth muscle cell (vSMC) proliferation by oral anti-hyperglycemic agents may have a role to play in the amelioration of vascular disease in diabetes.
de Dios Stephanie T +5 more
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EBioMedicine, 2019 Background: TK2 is a nuclear gene encoding the mitochondrial matrix protein thymidine kinase 2 (TK2), a critical enzyme in the mitochondrial nucleotide salvage pathway.
Carlos Lopez-Gomez +9 more
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Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major. [PDF]
PLoS Neglected Tropical Diseases, 2015 Leishmania spp. is a protozoan parasite and the causative agent of leishmaniasis. Thymidine kinase (TK) catalyses the transfer of the γ-phosphate of ATP to 2'-deoxythymidine (dThd) forming thymidine monophosphate (dTMP). L.
Jennifer Timm +6 more
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Concentration of human thymidine kinase 1 discover invisible malignant human tumours
European Journal of Cell Biology, 2022 Early discover of risk progression of invisible carcinomas is important for a prerequisite successful treatment. Here, we investigated whether concentration of human thymidine kinase 1 (HTK1) discover invisible malignant human tumours.
Ji Zhou +10 more
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Thymidine Kinase in IDU Resistance.
Experimental Biology and Medicine, 1965 SummaryStudies were done to determine whether 5-iodo-2′-deoxyuridine resistance of herpes simplex in rabbit corneal infection was a function of thymidine kinase deficiency in the viral genome. Herpes simplex virus passed in rabbit kidney cells in the presence of 5-iodo-2′-deoxyuridine was resistant to it in vivo although this resistant virus induced ...
Y, Centifanto, H E, Kaufman
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