Results 61 to 70 of about 228,294 (294)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

CURRENT TRENDS ON RUSSIAN FURNITURE MARKET AND POSSIBLE COMPETITIVENESS STRATEGIES OF FURNITURE-MAKING ENTERPRISES

Вестник Российского экономического университета имени Г. В. Плеханова, 2019
Furniture-making industry manufacturing consumer goods takes one of the key positions among industries of the timber-merchant complex of the Russian Federation.
Vitaliy A. Zhigarev
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Implementasi Augmanted Reality sebagai Media Pengenalan Sains Sederhana Pada Anak Usia Dini

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2018
This study aims to determine the increasing knowledge of simple science in Early Childhood in Kindergarten-right Aisyiyah Batusangkar after using Augmanted Reality technology as learning media. The type of research conducted is classroom action research.
Erna Erna
doaj   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Kemampuan Berhitung Anak melalui Media Kartu Angka

Aṭfālunā, 2019
This research was conducted due to the low level of numeracy ability in children of group B in TK Kemala Bhayangkari 13 Padangsidimpuan. The formulation of the problem under study was how to improve children's numeracy skills through numeric media.
Dina Marselani
doaj   +1 more source

Digital transformation of the world market of aviation services

E-Management, 2020
The article is devoted to the analysis of the key effects of digital transformation for the development of the modern world market of aviation services. The long-term international competitiveness of airlines will be determined by the use of a wide range
F. Baykov
doaj   +1 more source

AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study.

Molecular Therapy, 2004
Malignant glioma is a devastating brain tumor with no effective treatment. This randomised, controlled study involved 36 patients with operable primary or recurrent malignant glioma. Seventeen patients were randomized to receive AdvHSV-tk gene therapy (3
A. Immonen, M. Vapalahti, K. Tyynelä, Heleena Hurskainen, A. Sandmair, R. Vanninen, G. Langford, N. Murray, S. Ylä-Herttuala   +8 more
semanticscholar   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Complete Regression of Metastatic Renal Cell Carcinoma by Multiple Injections of Engineered Mesenchymal Stem Cells Expressing Dodecameric TRAIL and HSV-TK

Clinical Cancer Research, 2012
Purpose: Durable complete remission of metastatic renal cell carcinoma (RCC) has rarely been achieved with current treatment modalities. To solve this problem, alternative therapeutic options with high efficacy and minimal side effects are strongly ...
Sae Won Kim, Su Jin Kim, Sang Hoon Park, H. Yang, Moon Cheol Kang, Young Woo Choi, Seong Muk Kim, S. Jeun, Y. Sung   +8 more
semanticscholar   +1 more source