Results 21 to 30 of about 5,768 (162)
Frontiers in Physiology, 2019 Aim: The physiological realities between Taekwondo (TKD) simulation kicking training and TKD competition according to the Olympic time frame remain unclear.
Sheng-Ju Chuang +4 more
doaj +1 more source
Co-occurrence of FLT3-TKD and NPM1 mutations defines a highly favorable prognostic AML group
Blood Advances, 2017 : Although FLT3 internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) confer an adverse prognosis, co-occurrence with a nucleophosphomin (NPM1) mutation partially improves response and survival outcomes.
Prajwal Boddu +9 more
doaj +1 more source
A dual inhibitor overcomes drug-resistant FLT3-ITD acute myeloid leukemia
Journal of Hematology & Oncology, 2021 FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor prognosis. Multiple FLT3 inhibitors are in various stages of clinical evaluation.
Peihong Wang +9 more
doaj +1 more source
Results in Chemistry, 2022 Epidermal growth factor receptor tyrosine kinase domain (EGFR-TKD) plays a crucial role in the onset and progression of different types of cancers. The existing EGFR-TKD inhibitors have many adverse side effects, which make them unsuitable to be used as ...
Showkat Ahmad Mir +3 more
doaj +1 more source
Spatial Resolutions of On-Axis and Off-Axis Transmission Kikuchi Diffraction Methods
Applied Sciences, 2019 Spatial resolution is one of the key factors in orientation microscopy, as it determines the accuracy of grain size investigation and phase identification.
Yitian Shen +7 more
doaj +1 more source
Molecular Dynamic Simulations and Binding Free Energy Evaluations of Thiazolo-[2,3-b] Quinazolinone Derivatives With wtEGFR-TKD and "TMLR" Mutant EGFR-TKD [PDF]
, 2021 Abstract Cancer causes innumerable deaths every year globally. Breast cancer and non-small cell lung carcinoma (NSCLC) are the most prevalent worldwide. The epidermal growth factor receptor tyrosine kinases play a pivotal role in manifestations of cellular signals in carcinoma cells and thus are endorsed as therapeutic targets in cancer ...
Showkat Mir, Binata Nayak
openaire +1 more source
Mapping Nanoscale Buckling in Atomically Thin Cr2Ge2Te6
Advanced Functional Materials, EarlyView.Atomic‐resolution STEM is used to resolve nanoscale buckling in monolayer Cr2Ge2Te₆. A noise‐robust image analysis reconstructs three‐dimensional lattice distortions from single plan‐view images, revealing pronounced defect‐driven nm‐scale out‐of‐plane buckling.
Amy Carl +20 more
wiley +1 more source
On the depth resolution of transmission Kikuchi diffraction (TKD) analysis [PDF]
Ultramicroscopy, 2019 In this paper, we have analysed the depth resolution that can be achieved by on-axis transmission Kikuchi diffraction (TKD) using a Zr-Nb alloy. The results indicate that the signals contributing to detectable Kikuchi bands originate from a depth of approximately the mean free path of thermal diffuse scattering (lambdaTDS) from the bottom surface of a ...
Liu, Junliang +3 more
openaire +3 more sources