Results 31 to 40 of about 7,528 (209)
Frontiers in Physiology, 2019 Aim: The physiological realities between Taekwondo (TKD) simulation kicking training and TKD competition according to the Olympic time frame remain unclear.
Sheng-Ju Chuang +4 more
doaj +1 more source
Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B Cells and NKT Cells. [PDF]
PLoS ONE, 2016 Previous studies from Multhoff and colleagues reported that plasma membrane Hsp70 acts as a tumour-specific recognition structure for activated NK cells, and that the incubation of NK cells with Hsp70 and/or a 14-mer peptide derived from the N-terminal ...
Ilona Hromadnikova +3 more
doaj +1 more source
A dual inhibitor overcomes drug-resistant FLT3-ITD acute myeloid leukemia
Journal of Hematology & Oncology, 2021 FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor prognosis. Multiple FLT3 inhibitors are in various stages of clinical evaluation.
Peihong Wang +9 more
doaj +1 more source
Results in Chemistry, 2022 Epidermal growth factor receptor tyrosine kinase domain (EGFR-TKD) plays a crucial role in the onset and progression of different types of cancers. The existing EGFR-TKD inhibitors have many adverse side effects, which make them unsuitable to be used as ...
Showkat Ahmad Mir +3 more
doaj +1 more source
Molecular Dynamic Simulations and Binding Free Energy Evaluations of Thiazolo-[2,3-b] Quinazolinone Derivatives With wtEGFR-TKD and "TMLR" Mutant EGFR-TKD [PDF]
, 2021 Abstract Cancer causes innumerable deaths every year globally. Breast cancer and non-small cell lung carcinoma (NSCLC) are the most prevalent worldwide. The epidermal growth factor receptor tyrosine kinases play a pivotal role in manifestations of cellular signals in carcinoma cells and thus are endorsed as therapeutic targets in cancer ...
Showkat Mir, Binata Nayak
openaire +1 more source
, 2021 In this paper, we describe the technique of on-axis transmission Kikuchi diffraction (TKD) in a scanning electron microscope and demonstrate its use in characterizing nanoscale crystal structures and defects in semiconductor materials and devices.
Goran, Daniel +2 more
core +1 more source
Practice-Changing Advances in Systemic Therapies Shaping the Landscape of Lung Cancer in 2025. [PDF]
Cancer InnovThis review synthesizes 2025 breakthroughs in systemic therapies of lung cancer, especially in targeted and immunotherapies, accelerating mortality decline across non‐small cell lung cancer and small cell lung cancer stages. ABSTRACT With the rapid advancement of molecular profiling and precision therapeutics, targeted and immunotherapeutic strategies ...
Zhou Z, Gao W, Li MSC, Zhou Q.
europepmc +2 more sources
Spatial Resolutions of On-Axis and Off-Axis Transmission Kikuchi Diffraction Methods
Applied Sciences, 2019 Spatial resolution is one of the key factors in orientation microscopy, as it determines the accuracy of grain size investigation and phase identification.
Yitian Shen +7 more
doaj +1 more source