Results 41 to 50 of about 5,768 (162)

Optical genome mapping detects cryptic high‐risk and targetable abnormalities in adult AML

British Journal of Haematology, EarlyView.
Summary Acute myeloid leukaemia (AML) risk stratification relies on cytogenetic and molecular abnormalities defined by European LeukemiaNet (ELN) 2022. Conventional cytogenetic techniques, including chromosomal banding analysis (CBA) and fluorescence in situ hybridization, have limited resolution and may miss cryptic events. Optical genome mapping (OGM)
Audrey Bidet, Elodie Laharanne, Manon Dos Santos, Anne‐Charlotte De Grande, Thibaut Leguay, Arnaud Pigneux, Eric Frison, Sandrine Achard, Stéphanie Dupont‐Moufakkir, Emilie Klein, Pierre‐Yves Dumas   +10 more
wiley   +1 more source

Bir Sivil Toplum Örgütü Olarak TKD

Türk Kütüphaneciliği, 2002
This conference paper was presented at the ÜNAK / URLA General Conference 10-12 October 2002, 19 Mayıs University, Samsun, organized by the ÜNAK / URLA Association.
openaire   +2 more sources

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Current perspectives on KMT2A fusion proteins and menin inhibition in paediatric acute myeloid leukaemia

The FEBS Journal, EarlyView.
Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets, Graeme Greenfield, Katrina Mairead Lappin   +2 more
wiley   +1 more source

Significance of Myelodysplasia‐Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia‐related (MR) mutations as defining of MDS‐related AML (AML‐MR).
Timothy J. Kirtek, Olga K. Weinberg
wiley   +1 more source

Tiletamine/Zolazepam and Ketamine with Dexmedetomidine (TKD) Cocktail Is as Effective as Tiletamine/Zolazepam and Ketamine with Xylazine (TKX) in Providing Pig General Anesthesia

Animals
This study aimed to evaluate dexmedetomidine as an alternative to xylazine in pigs. We compared TKD (0.05 mL/kg) to TKX (0.05 mL/kg) in 20 male pigs undergoing unilateral cryptorchid castration (short-term, 45-min) or bilateral cryptorchid castration ...
Ekkapol Akaraphutiporn, Sumit Durongphongtorn, Katechan Jampachaisri, Patrick Sharp, Cholawat Pacharinsak, Chalika Wangdee   +5 more
doaj   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Global Factors in Noncore Bank Funding and Exchange Rate Flexibility

Journal of Money, Credit and Banking, EarlyView.
Abstract We show that fluctuations in the ratio of noncore to core funding in the banking systems of advanced economies are largely driven by three global factors of both real and financial natures, with country‐specific factors playing only a minor role. Exchange rate flexibility helps insulate the noncore to core ratio from such global factors.
LUÍS A.V. CATÃO, JAN DITZEN, DANIEL MARCEL TE KAAT   +2 more
wiley   +1 more source

NASM-based Core Stability Training Using Taekwondo Movements in Male Individuals With Hyperlordosis [PDF]

Physical Treatments
Purpose: Hyperlordosis is a postural condition characterized by excessive lumbar spine curvature, often associated with pain and musculoskeletal dysfunction.
Ebrahim Ebrahimi, Seyed Morteza Tabatabaee, Afsaneh Dadarkhah, Sharif Najafi   +3 more
doaj  

Effects of creatine supplementation in taekwondo practitioners

Nutrición Hospitalaria, 2013
Introduction: Taekwondo (TKD) is a combat sport, which has also been proposed as a fitness program, with a strong anaerobic component. Creatine (Cr) supplementation is used to improve both anaerobic exercise performance and body composition.
Rafael Manjarrez-Montes de Oca, Fernando Farfán-González, Socorro Camarillo-Romero, Patricia Tlatempa-Sotelo, Carlos Francisco-Argüelles, Alexander Kormanowski, Javier González-Gallego, Ildefonso Alvear-Ordenes   +7 more
doaj   +1 more source