Results 51 to 60 of about 17,798 (188)

Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp-70-Derived 14-mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors

open access: yesMediators of Inflammation, 2013
NK cells represent a potential tool for adoptive immunotherapy against tumors. Membrane-bound Hsp70 acts as a tumor-specific marker enhancing NK cell activity.
Ilona Hromadnikova   +2 more
doaj   +1 more source

81030 Utilizing a synergistic drug combination to target relapsed/refractory FLT3 mutant AML

open access: yesJournal of Clinical and Translational Science, 2021
IMPACT: This work will help to understand a novel therapeutic approach to a common type of acute myeloid leukemia. OBJECTIVES/GOALS: FMS-like tyrosine kinase 3 (or FLT3) mutations occur in ˜30% of acute myeloid leukemia (AML) cases.
LaQuita Jones   +7 more
doaj   +1 more source

Constraints on Light WIMP candidates from the Isotropic Diffuse Gamma-Ray Emission

open access: yes, 2011
Motivated by the measurements reported by direct detection experiments, most notably DAMA, CDMS-II, CoGeNT and Xenon10/100, we study further the constraints that might be set on some light dark matter candidates, M_DM ~ few GeV, using the Fermi-LAT data ...
Arina, Chiara, Tytgat, Michel H. G.
core   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang   +4 more
wiley   +1 more source

Damping scales of neutralino cold dark matter [PDF]

open access: yes, 2005
The lightest supersymmetric particle, most likely the neutralino, might account for a large fraction of dark matter in the Universe. We show that the primordial spectrum of density fluctuations in neutralino cold dark matter (CDM) has a sharp cut-off due
Hofmann, Stefan   +2 more
core  

Galactic PeV neutrinos from dark matter annihilation

open access: yes, 2014
The IceCube Neutrino Observatory has observed highly energetic neutrinos in excess of the expected atmospheric neutrino background. It is intriguing to consider the possibility that such events are probing physics beyond the standard model.
Zavala, Jesus
core   +1 more source

Optical genome mapping detects cryptic high‐risk and targetable abnormalities in adult AML

open access: yesBritish Journal of Haematology, EarlyView.
Summary Acute myeloid leukaemia (AML) risk stratification relies on cytogenetic and molecular abnormalities defined by European LeukemiaNet (ELN) 2022. Conventional cytogenetic techniques, including chromosomal banding analysis (CBA) and fluorescence in situ hybridization, have limited resolution and may miss cryptic events. Optical genome mapping (OGM)
Audrey Bidet   +10 more
wiley   +1 more source

Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy – a case report

open access: yesJournal of Translational Medicine, 2009
Background Membrane-bound heat shock protein 70 (Hsp70) serves as a tumor-specific recognition structure for Hsp70-peptide (TKD) plus IL-2 activated NK cells.
Hube Kathrin   +9 more
doaj   +1 more source

The surface brightness profile of the remote cluster NGC 2419

open access: yes, 2007
It is well known that the bright and remote Galactic globular cluster NGC2419 has a very peculiar structure. In particular its half-light radius is significantly larger than that of ordinary globular clusters of similar luminosity, being as large as that
Bellazzini, Michele
core   +1 more source

Bir Sivil Toplum Örgütü Olarak TKD

open access: yesTürk Kütüphaneciliği, 2002
This conference paper was presented at the ÜNAK / URLA General Conference 10-12 October 2002, 19 Mayıs University, Samsun, organized by the ÜNAK / URLA Association.
openaire   +2 more sources

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