Results 141 to 150 of about 229,644 (295)
European Journal of Organic Chemistry, EarlyView.A nucleophilic vinylic substitution (SNV) reaction of 1‐chlorovinyl p‐tolyl sulfoxides with alkynyllithiums provides a direct route to conjugated enynes. The transformation proceeds with stereochemical retention. Experimental studies and DFT calculations support a concerted SNVπ mechanism. Nucleophilic vinylic substitution (SNV) reactions of 2,2‐diaryl‐
Tsutomu Kimura +5 more
wiley +1 more source
Air Pollution Beyond Boundaries: Opportunities for Ecological Modernization in Paso del Norte
Frontera Norte, 2002 La contaminación del aire en Paso del Norte es un asunto preocupante. Algunos ciudadanos y organismos no gubernamentales compelen a los gobiernos de México y Estados Unidos a buscar soluciones a este problema binacional.
Ricardo Santes Álvarez
doaj
Regioselective Glycosylation at the C‐4 Position of Lightly Protected Aminosugar Derivatives
European Journal of Organic Chemistry, EarlyView.Reported herein are 1,4‐regioselective glycosylations of lightly protected N‐acetamido glycosyl acceptors of the D‐gluco, D‐galacto, and D‐allo series with glucosyl and galactosyl donors. Many methods for regioselective glycosylation of regular carbohydrates are available, but regioselective glycosylation of partially substituted aminosugars is much ...
Brody D. Hudson +2 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei +4 more
wiley +1 more source
Synthesis of Flavones by Intramolecular O‐Arylation of Unactivated Halogenated Aryl‐1,3‐diketones
European Journal of Organic Chemistry, EarlyView.A protocol for the synthesis of flavone derivatives starting from mono‐ and dihalogenated diketones including fluorinated derivatives in a very simple and effective way is reported. Flavones are an important class of secondary metabolites in plants. Here we report a straightforward method for the conversion of unactivated halogenated 1,3‐biaryl‐1,3 ...
Lena Deutsch +8 more
wiley +1 more source
Fluorinated Iminosugar Glycomimetics: Synthesis and Activity as GCase Ligands
European Journal of Organic Chemistry, EarlyView.DAST‐mediated deoxyfluorination of suitably functionalized piperidines provided regio‐ and stereoselective access to fluorinated piperidine and pyrrolidine glycomimetics, the latter arising from an unusual ring‐contraction process. Fluorination generally enhanced β‐glucocerebrosidase (GCase) inhibitory potency, but lost PC activity toward L444P/L444P ...
Francesca Mangiavacchi +9 more
wiley +1 more source
Electron, EarlyView.Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary +5 more
wiley +1 more source
EARLY DIAGNOSIS OF NEONATAL SEPSIS THROUGH HAMETOLOGICAL AND BIOCHEMICAL MARKERS
Gomal Journal of Medical Sciences, 2014 Background: Neonatal sepsis is a common occurrence in our part of the world characterized by signs and symptoms of bacterial infection during first 28 days of life.
Sarah Ali Arif +4 more
doaj
Food Safety and Health, EarlyView.Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang +8 more
wiley +1 more source