Results 81 to 90 of about 337,656 (329)

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo   +14 more
wiley   +1 more source

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

open access: yesAdvanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou   +4 more
wiley   +1 more source

Detection and Quantitation of Aflatoxin for the Diagnosis of Aspergillus flavus

open access: yesNepal Journal of Biotechnology, 2015
Aflatoxins are the potent mycotoxins produced by Aspergillus flavus, which is hepatotoxic causing hepatocellular carcinoma. A. flavus produces sufficient amount of Aflatoxin B1 under favourable environments.
Geeta Rajbhandari Shrestha   +1 more
doaj   +1 more source

In search of place for the trainee teacher: how can geography departments most benefit from welcoming trainee teachers? [PDF]

open access: yes, 2012
The article explores various interpretations of how to position trainee teachers within their geography departments following the narrative of the authors' own professional career from Head of Geography in a school to doctoral researcher at University ...
Rosenthal, Robert
core   +1 more source

Secalonic acid A from Pseudoparmelia sphaerospora (Nyl.) Hale and P. hypomilta (Fée) Hale (Parmeliaceae) [PDF]

open access: yes, 1995
Secalonic acid A, a yellow pigment from fungal metabolism, was isolated from the lichens Pseudoparmelia sphaerospora and P. hypomilta. From P. sphaerospora was also isolated the depsidone hypostictic acid.
Devincenzi, Izilda A. A.   +2 more
core   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Molecular identification and phytochemical profiling of kamiling (wild toxic plant) using thin layer chromatography

open access: yesInternational Journal of Secondary Metabolite, 2018
Some plants may only be known by the people in their own respective place. Consequently, there is a need for the authentication and further study of wild toxic plant known by indigenous people.
Dana Theresa C. De Leon   +3 more
doaj   +1 more source

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

open access: yesAdvanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li   +5 more
wiley   +1 more source

Tlc [PDF]

open access: yesOrganic Process Research & Development, 2005
Teresa Kowalska, Wojciech Prus
openaire   +2 more sources

Isolation and functional analysis of cDNAs similar to Hyp-1 involved in hypericin biosynthesis from Hypericum erectum

open access: yesBiologia Plantarum, 2010
Hypericin, a naphthodianthrone, has been identified as the principal active compound found in St. John's wort (Hypericum perforatum L.). To generate a gene resource for hypericin and other valuable metabolites, we generated expressed sequence tags (ESTs)
M. L. Jin   +5 more
doaj   +1 more source

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