Results 41 to 50 of about 1,281 (202)

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

Mesenteric Lymphatic Dysfunction as the Initiating Event in Crohn's Disease: Toward an Outside‐In Paradigm

open access: yesJCC Plus, Volume 1, Issue 4, July 2026.
Mesenteric lymphatic dysfunction promotes immune cell accumulation and chronic inflammation, leading to creeping fat formation. Progressive activity drives transmural inflammation. ABSTRACT Crohn's disease (CD) has traditionally been explained by an “inside‐out” model, in which disruption of the intestinal mucosal barrier allows luminal bacteria to ...
Takayuki Ogino   +9 more
wiley   +1 more source

Development of Mucosal PNAd+ and MAdCAM-1+ Venules during Disease Course in Ulcerative Colitis

open access: yesCells, 2020
PNAd and MAdCAM-1 addressins on venules are of importance in T-cell homing and potential therapeutic targets in ulcerative colitis (UC). Normally, PNAd+ high endothelial venules (HEVs) are only present in lymphoid organs, whereas small numbers of MAdCAM ...
Britt Roosenboom   +10 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Metabarcoding of Sediment eDNA Uncovers Ecological Gradients and Biodiversity in Philippine Mangroves

open access: yesEnvironmental DNA, Volume 8, Issue 3, May–June 2026.
Community diversity metrics revealed a clear ecological gradient, with the highest diversity observed in recolonized mature stands, intermediate in the natural stands, and lowest in the restored stands. Taxonomic profiles varied with mangrove stand, age, and zonation.
Severino G. Salmo III   +3 more
wiley   +1 more source

Development and implementation of a remote patient monitoring program for heart failure: a single‐centre experience

open access: yesESC Heart Failure, 2021
Aims Remote patient monitoring (RPM) in the management of heart failure (HF), including telemonitoring, thoracic impedance, implantable pulmonary artery pressure (PAP) monitors, and cardiac implantable electronic device (CIED)‐based sensors, has had ...
Bryana N. Baginski   +6 more
doaj   +1 more source

Clinical and Socioeconomic Predictors of 60‐Day Rehospitalization After Oncologic Head and Neck Surgery

open access: yesOtolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1270-1278, May 2026.
Abstract Objective Evaluate the association between clinical characteristics and neighborhood socioeconomic disadvantage and 60‐day re‐presentation after oncologic head and neck surgery. Study Design This retrospective cohort study involved 1,088 patients who underwent oncologic head and neck surgery from August 2012 to November 2024.
Nana‐Hawwa Abdul‐Rahman   +3 more
wiley   +1 more source

Goat at Tlos

open access: yes, 2015
Goat at Tlos, an ancient ruined Lycian hilltop citadel which is near the resort town of Kalkan in the Antalya Province of southern Turkey, located on the east side of the Xanthos valley atop an rocky outcrop that slopes up from a plateau from a modern ...
Gonnet-Bağana, Hatice
core   +1 more source

Implementing the Threshold Learning Outcomes for Agriculture at university

open access: yesJournal of Teaching and Learning for Graduate Employability, 2016
The national Learning and Teaching Academics Standards statement for agriculture (AgLTAS) defines the nature and extent of the discipline; and provides threshold learning outcomes (TLOs) that define what a graduate should know, understand and do at ...
Tina Acuna   +3 more
doaj   +1 more source

Performance of eight soil moisture sensors as affected by soil texture and electrical conductivity

open access: yesVadose Zone Journal, Volume 25, Issue 3, May/June 2026.
Abstract Accurate soil moisture information helps farmers, ranchers, and land managers make informed decisions, and this information often comes from in situ measurements. In situ sensors operate based on a variety of technologies, and there is an ongoing need to determine the accuracy of these sensors across different soils.
William G. Brown   +3 more
wiley   +1 more source

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