Results 261 to 270 of about 300,160 (284)
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Current Opinion in Pharmacology, 2011
Toll-like receptors (TLRs) play a crucial role in innate immune responses to infection. Binding of agonists to TLRs promotes maturation of antigen presenting cells, such as dendritic cells, which in turn directs the induction of adaptive immune responses.
Aisling, Dunne +2 more
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Toll-like receptors (TLRs) play a crucial role in innate immune responses to infection. Binding of agonists to TLRs promotes maturation of antigen presenting cells, such as dendritic cells, which in turn directs the induction of adaptive immune responses.
Aisling, Dunne +2 more
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Seminars in Immunology, 2004
Toll-like receptors (TLRs) have been established to play an essential role in the activation of innate immunity by recognizing specific patterns of microbial components. TLR signaling pathways arise from intracytoplasmic TIR domains, which are conserved among all TLRs.
Kiyoshi, Takeda, Shizuo, Akira
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Toll-like receptors (TLRs) have been established to play an essential role in the activation of innate immunity by recognizing specific patterns of microbial components. TLR signaling pathways arise from intracytoplasmic TIR domains, which are conserved among all TLRs.
Kiyoshi, Takeda, Shizuo, Akira
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TLR signalling and association of TLR polymorphism with cardiovascular diseases
Vascular Pharmacology, 2016Toll-Like receptors (TLRs) are the primary receptors of innate immunity. Considerable evidences have shown that innate immune defence interaction with pro-inflammatory pathways could be through TLRs that in turn leads to development of inflammatory diseases. These TLRs are present on various tissues and cells of cardiovascular system.
Swati, Sharma +2 more
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Archives of Medical Research, 2011
Few studies have examined the presence of Toll-like receptors (TLRs) in term placentas from women with preeclampsia, such, have focused on TLR-4 and TLR-2 analysis. Whereas an increase in TLR-4 immunostaining has been observed in preeclampsia, it is even higher in placentas with chorioamnionitis compared with normal pregnancy.
Antonio, Pineda +3 more
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Few studies have examined the presence of Toll-like receptors (TLRs) in term placentas from women with preeclampsia, such, have focused on TLR-4 and TLR-2 analysis. Whereas an increase in TLR-4 immunostaining has been observed in preeclampsia, it is even higher in placentas with chorioamnionitis compared with normal pregnancy.
Antonio, Pineda +3 more
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TLR Signaling in Brain Immunity
2021Toll-like receptors (TLRs) comprise a group of transmembrane proteins with crucial roles in pathogen recognition, immune responses, and signal transduction. This family represented the first line of immune homeostasis in an evolutionarily conserved manner.
Mengdi, Guo, Yun, Xu, Cun-Jin, Zhang
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Nature Reviews Immunology, 2019
Two papers by Gregory Barton and colleagues identify distinct UNC93B1-dependent mechanisms for regulation of the endosomal nucleic acid-sensing TLRs, TLR7 and TLR9.
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Two papers by Gregory Barton and colleagues identify distinct UNC93B1-dependent mechanisms for regulation of the endosomal nucleic acid-sensing TLRs, TLR7 and TLR9.
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Science Signaling, 2011
Signaling through innate immune receptors promotes commensal bacteria colonization of the gut.
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Signaling through innate immune receptors promotes commensal bacteria colonization of the gut.
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Science Signaling, 2011
Major histocompatibility class II molecules promote Toll-like receptor signaling in macrophages and dendritic cells.
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Major histocompatibility class II molecules promote Toll-like receptor signaling in macrophages and dendritic cells.
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2016
OBJECTIVE: Toll-like receptors (TLRs) are the transmembrane proteins, which recognize highlyconserved structural motifs known as pathogen-associated microbial patterns (PAMPs), which areexclusively expressed by bacterial, fungal and viral pathogens. TLRs play key role in both ininitiating the innate immune response and in the regulation of adaptive ...
Liman, Narin, Alan, Emel
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OBJECTIVE: Toll-like receptors (TLRs) are the transmembrane proteins, which recognize highlyconserved structural motifs known as pathogen-associated microbial patterns (PAMPs), which areexclusively expressed by bacterial, fungal and viral pathogens. TLRs play key role in both ininitiating the innate immune response and in the regulation of adaptive ...
Liman, Narin, Alan, Emel
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[The role of TLR-2, TLR-3, TLR-4 genes polymorphism of grippe].
Georgian medical news, 2015Distribution and prognostic value of Arg753Gln TLR-2, Leu412Рhe TLR-3, Asp299Gly TLR-4 genes polymorphism in case of grippe have been studied in the present article. The examination has comprised 112 patients with grippe including 63 cases with uncomplicated course and 49 cases with grippe-associated pneumonia. The population control group has included
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