Results 331 to 340 of about 274,305 (384)

Bronchial Fibroblasts Respond to House Dust Mite Challenge With Cytokine Secretion: Role in Allergic Airway Inflammation

iMetaMed, EarlyView.
Schematic of the early‐stage characteristics of house dust mites‐induced bronchial fibroblasts, which are characterized by suppressed extracellular matrix production alongside activated inflammatory signaling.
Dong Zhang, Wei Liu, Tao Wang, Xiaozhi Wang, Qian Qi   +4 more
wiley   +1 more source

The innate immune response in SARS-CoV2 infection: focus on toll-like receptor 4 in severe disease outcomes. [PDF]

Front Immunol
Maggi E, Landolina N, Mariotti FR, Munari E, Tumino N, Vacca P, Azzarone B, Moretta L.   +7 more
europepmc   +1 more source

Dynamics and Regulation of Maternal–Fetal Interface Macrophages: From Immune Tolerance to Pregnancy Outcomes

iMetaMed, EarlyView.
The maternal–fetal interface demands tolerance alongside antimicrobial defense. Plastic macrophages orchestrate inflammation resolution, tissue remodeling, and angiogenesis in normal gestation; complications (miscarriage, preterm birth) feature polarization skewing and dysfunction.
Xinyue Wang, Haochen Yang, Yunzhao Xu, Jinling Chen   +3 more
wiley   +1 more source

The EZH2 Inhibitor GSK126 Alleviates Thromboinflammation in Deep Vein Thrombosis by Suppressing TLR4 Signaling via H3K27me3 Modulation. [PDF]

J Inflamm Res
Zhou R, Luo J, Zheng H.
europepmc   +1 more source

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

iMeta, EarlyView.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu, An‐Jun Wang, De‐Chao Bu, Yan‐Yan Sun, Chen‐Hao Li, Yue‐Mei Hong, Shan Zhang, Shi‐Yang Chen, Jin‐An Zhou, Tian‐Yi Zhang, Min‐Hao Yu, Yong‐Jing Ma, Xiu‐Li Wang, Jia Xu, Wei He, Christopher Heeschen, Jian‐Feng Chen, Wen‐Jun Mao, Hui Ding, Wen‐Juan Wu, Yi Zhao, Hui Wang, Ning‐Ning Liu   +22 more
wiley   +1 more source

Dualistic Roles of High Mobility Group Box 1 in Cancer and Inflammation. [PDF]

Cancer Med
Zeng W, Zhang X, Jiang Y, Luo Y, Wang Z, Du X, Chen L.   +6 more
europepmc   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei, Hamid Pajavand, Razieh Shahbazi, Marzieh Rezaei, Elahe Taki   +4 more
wiley   +1 more source

Toxoplasma gondii-induced adverse pregnancy outcomes: insight into the inhibitory role of Trem2 on TLR4/TRAF6/JNK signaling pathway. [PDF]

Parasit Vectors
Cao Y, Fu F, Ju F, Wu C, Yao T, Yang M, Sun B, Chen J.   +7 more
europepmc   +1 more source

Genetic Evidence Implicating Gut Microbiota and Circulating Cytokines in Sjögren's Syndrome

Journal of Clinical Laboratory Analysis, EarlyView.
Complex bidirectional causal relationships were found between gut microbiota abundance and Sjögren's syndrome (SS). Five circulating cytokines were shown to potentially affect SS, including MIG, IL‐5, IL‐1RA, IL‐2RA, and SCGF‐β, and SS was found to increase levels of two circulating cytokines, IL‐1β and IL‐5.
Yuchen Cai, Tianyi Zhou, Wenjun Shi, Xia Ding, Xueyao Cai, Li Yu   +5 more
wiley   +1 more source

Metformin Inhibits Microglial Activation-Mediated Cuproptosis by Modulating the TLR4/Myd88/NF-κB Signaling Pathway in Parkinson's Disease. [PDF]

Mol Neurobiol
Shang H, Wang Z, Sun Y, Zuo C, Wang M, Zheng K, Wang Y, Zhu J.   +7 more
europepmc   +1 more source